Intradural/Extramedullary Lesion, T1 Hypointense



Intradural/Extramedullary Lesion, T1 Hypointense


Jeffrey S. Ross, MD



DIFFERENTIAL DIAGNOSIS


Common



  • CSF Flow Artifact


  • Post-Operative Intrathecal Gas


  • Metal Artifact


  • Arachnoid Cyst


  • Epidermoid


  • Meningioma, Calcified


  • Schwannoma, Cystic


  • Vascular Malformation


Less Common



  • CSF Disseminated Metastases


  • Displaced Cord with Prominent Adjacent CSF



    • Spinal Cord Herniation


    • Arachnoiditis/Adhesion


    • Post-Traumatic Pseudomeningocele


  • Arachnoiditis Ossificans


  • Cysticercosis


  • Ependymoma, Myxopapillary (Calcified)


  • Glioma, Exophytic


Rare but Important



  • Neurenteric Cyst


ESSENTIAL INFORMATION


Helpful Clues for Common Diagnoses



  • CSF Flow Artifact



    • Linear or rounded low signal with ill-defined margins surrounding cord due to normal CSF motion


    • Typically most prevalent in dorsal thoracic spine


    • Include axial GE images to minimize artifact and exclude vascular flow voids


  • Metal Artifact



    • Geometric distortion and signal loss secondary to dephasing


    • T1 images show focal central signal loss with peripheral “halo” of ↑ signal related to spatial mismapping


    • Image quality: Fast spin echo > conventional spin echo < gradient echo


    • Smaller voxel size, lower field strength decrease artifact amount


    • Appropriate geometric orientation of frequency encode direction parallel to pedicle screws shows thecal sac best


  • Arachnoid Cyst



    • Nonenhancing extramedullary loculated CSF intensity collection displacing cord or nerve roots


    • May be suggested by mass effect on cord and nerve roots without direct wall visualization


    • Partial filling of cyst may occur with CT myelography, with wind-sock type


  • Epidermoid



    • Nonenhancing intradural mass similar to CSF intensity within cauda equina


    • Should not track CSF on all pulse sequences, as would arachnoid cyst


    • Should not enhance, unless complicated by infection


    • If lumbar in child, look for associated dermal sinus track


  • Meningioma, Calcified



    • Enhancing intradural/extramedullary mass and dural tail


    • Calcified lesions may show little enhancement, very low T1/T2 signal


    • May show target pattern with central calcification, peripheral homogeneous tumor enhancement


  • Schwannoma, Cystic



    • Well-circumscribed, dumbbell-shaped, enhancing spinal mass


    • May be solid, yet show T1 homogeneous hypointensity


    • T1 hypointensity may also reflect cyst formation


  • Vascular Malformation



    • Serpentine flow voids with well-defined margins


    • Variable pattern depending upon type (fistula vs. AVM) and location (cord vs. pial vs. transpatial)


    • Most common is type 1, with vessels on dorsal cord surface with cord T2 hyperintensity due to venous hypertension


Helpful Clues for Less Common Diagnoses



  • CSF Disseminated Metastases



    • Smooth/nodular enhancement along cord, roots is best clue


    • Without contrast, leptomeningeal mets may show ill-defined cord & cauda with “dirty” CSF appearance


  • Spinal Cord Herniation



    • Herniation of spinal cord through defect in dura of ventral canal



    • Focal anterior displacement of cord with expansion of dorsal subarachnoid space in upper thoracic spine


    • Distinguish from posterior arachnoid cyst by more abrupt cord deformity with idiopathic herniation


  • Arachnoiditis/Adhesion



    • Focal tethering of cord to dura from prior surgery, infection, or SAH


    • Shown by distortion of location and morphology of cord within thecal sac


    • May be associated with arachnoid cysts, superficial siderosis, cord edema


  • Post-Traumatic Pseudomeningocele



    • CSF collection typically associated with upper cervical fracture (odontoid) with ventral CSF collection and displacement of cord posteriorly


    • Multisegmental posterior displacement of cervical cord in face of significant cervical trauma


    • Distinguish from acute epidural hemorrhage that shows isointense T1 signal, heterogeneous T2 signal


  • Arachnoiditis Ossificans



    • Uncommon presentation of arachnoiditis due to prior trauma, lumbar surgery, subarachnoid hemorrhage, myelography, spinal anesthesia


    • End-stage arachnoiditis with diffuse or nodular low signal on all pulse sequences involving dura and cord surface, cauda equina


  • Cysticercosis



    • CNS parasitic infection caused by pork tapeworm, Taenia solium


    • Intradural cyst with evidence of similar lesions in brain most helpful clue


    • Parenchymal, leptomeningeal, intraventricular, spinal form with cyst size up to 2 cm


  • Exophytic Intramedullary Tumor



    • Solid exophytic component may mimic ID/EM lesion


    • Look for contiguous extension into cord on sagittal/axial planes


    • Contrast enhancement may show contiguous nature of intramedullary mass

Aug 7, 2016 | Posted by in NEUROLOGY | Comments Off on Intradural/Extramedullary Lesion, T1 Hypointense

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