Duplication of the Pituitary Gland

Fig. 69.1

Duplication of the pituitary gland. (a) Sagittal T1-weighted MR scan shows hypothalamic thickening (arrow). (b) Coronal T1-weighted MR scan shows two separate anterior and posterior pituitary glands with two separate pituitary stalks (arrows) (Adapted with permission from Akin et al. [14])

69.3 Clinical Management

Treatment in patients with duplicated pituitary glands is highly individualized. Treatment may not be necessary. When it is needed, treatment includes screening for and management of precocious puberty and treatment of any associated tumors.

References

Slavotinek A, Parisi M, Heike C, Hing A, Huang E. Craniofacial defects of blastogenesis: duplication of pituitary with cleft palate and orophgaryngeal tumors. Am J Med Genet A. 2005;135:13–20.CrossRefPubMed

Hamon-Kérautret M, Ares GS, Demondion X, Rouland V, Francke JP, Pruvo JP. Duplication of the pituitary gland in a newborn with median cleft face syndrome and nasal teratoma. Pediatr Radiol. 1998;28:290–2.CrossRefPubMed

Chariker M, Ford R, Morrison C, Theile A, Moeller K, Moriarty T. Pituitary duplication with nasopharyngeal teratoma and cleft palate. J Craniofac Surg. 2011;22:755–8.CrossRefPubMed

Huisman TA, Fischer U, Boltshauser E, Straube T, Gysin C. Pituitary duplication and nasopharyngeal teratoma in a newborn: CT, MRI, US and correlative histopathological findings. Neuroradiology. 2005;47:558–61.CrossRefPubMed

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