Intraoperative Functional Mapping George A. Ojemann Susan Y. Bookheimer Introduction This chapter describes established intraoperative methods for identifying functionally important cortex during resective epilepsy surgery. Several other chapters are complementary….
Intraarterial Amobarbital Procedures Marilyn Jones-Gotman Mary Lou Smith Heinz Gregor Wieser Introduction Successive hemianesthesia of the two cerebral hemispheres elicited by injection of an anesthetic agent into the internal carotid…
Intraoperative Electrocorticography Mark D. Holmes Gian-Emilio Chatrian Introduction The method of recording electrical potentials directly from the cerebral cortex (electrocorticography [EcoG]) or from the cerebral cortex and subjacent structures was…
Intracranial Electrodes Susan S. Spencer Michael R. Sperling D. Alan Shewmon Philippe Kahane Introduction Reports and experience worldwide have shown that resection of the epileptogenic area of brain in uncontrolled…
Foramen Ovale and Peg Electrodes Heinz Gregor Wieser Introduction The foramen ovale (FO) electrode recording technique was developed in Zürich in 1983.26 Its goal was to make less invasive and…
Presurgical Evaluation: General Principles and Methods Gary W. Mathern Michael R. Sperling Introduction Epilepsy surgery is considered when seizures are incompletely controlled by medication and it is apparent that further…
Surgically Remediable Syndromes Jerome Engel Jr. Gregory D. Cascino W. Donald Shields Introduction The safety and efficacy of surgical treatment for epilepsy have improved greatly in recent years as a…
Indications and Criteria for Surgical Intervention Michael S. Duchowny A. Simon Harvey Michael R. Sperling Peter D. Williamson Introduction The estimated lifetime cumulative incidence and prevalence of epilepsy are 3%…
Overview: Surgical Therapy Jerome Engel Jr. Heinz Gregor Wieser Dennis D. Spencer Introduction Surgical treatment for epilepsy has a long and distinguished history.11,15,33 Trephination was practiced since prehistoric times in…
Immunoglobulin and Immunomodulatory Therapy Flavio Villani Christian G. Bien Giuliano G. Avanzini Introduction The use of immunoglobulin in intractable epilepsy is one of its oldest applications in medicine, starting from…
