Supratentorial Primitive Neuroectodermal Tumors (PNETs)
Fig. 8.1 MRI study of a 28-year old male with pineoblastoma. (a) Axial CT scan without contrast: The sharply demarcated tumor is hyperdense in CT images. Hydrocephalus is also evident….
Management of Hemangiopericytoma
(1) Department of Neurosurgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan Takenori Akiyama Email: akiyamanor@gmail.com Introduction Pathological Findings Radiographical Features Clinical Course Presurgical Embolization Surgery Surgical Concept Radiation…
Embryonal Tumor: Molecular Characterization
Fig. 1.1 Neuroblastic tumor containing abundant neuropil and true rosettes. These tumors characteristically show numerous rosettes, i.e. ependymoblastic (a) and Homer-Wright (b). HE; original magnification (a, b) ×200 Atypical Teratoid…
Neonatal Hypoxic-Ischemic Brain Damage: Human Umbilical Cord Blood Mononuclear Cells Transplantation
Model (animal, duration of hypoxia) Dose; route; timing Engraftment (days after transplantation) Functional outcome Cellular/molecular effects References P7 Wistar rats, 80 min 1 × 107 cells, IP; 24 h after HI Large…
Immunotherapies for Brain Cancer: From Preclinical Models to Human Trials
Fig. 25.1 Local administration of Ad-TK+Ad-Flt3L enhances the therapeutic efficacy of systemic antitumor DC vaccines. (a) DC vaccines were obtained from bone marrow precursors incubated in the presence of Flt3L,…
Alexander Disease: Role of Glial Fibrillary Acidic Protein
Fig. 22.1 Schematic depicting the GFAP gene, the corresponding protein and localization of GFAP mutations identified in patients with Alexander disease The R416W GFAP mutation is located in the tail…
Differentiating Choroid Plexus Tumors from Metastatic Carcinomas: Use of Inwardly Rectifying K+ Channel KIR7.1 and Excitatory Amino Acid Transporter-1
M.A. Hayat (ed.)Tumors of the Central Nervous SystemTumors of the Central Nervous System, Volume 132014Types of Tumors, Diagnosis, Ultrasonography, Surgery, Brain Metastasis, and General CNS Diseases10.1007/978-94-007-7602-9_21 © Springer Science+Business Media Dordrecht 2014 21. Differentiating…
The Role of Surgical Resection for Metastatic Brain Tumors
Evidence classification Class I Evidence provided by one or more well-designed randomized controlled clinical trials, including overview (meta-analyses) of such trials Class II Evidence provided by well-designed observational studies with…
Resection of Brain Tumors: Intraoperative Confocal Microscopy Technology
M.A. Hayat (ed.)Tumors of the Central Nervous SystemTumors of the Central Nervous System, Volume 132014Types of Tumors, Diagnosis, Ultrasonography, Surgery, Brain Metastasis, and General CNS Diseases10.1007/978-94-007-7602-9_16 © Springer Science+Business Media Dordrecht 2014 16. Resection…
Role of Cyclooxygenase-2 in the Development and Growth of Schwannomas
Fig. 5.1 COX-2 induces tumor angiogenesis via multiple pathways (Gately and Li 2004; reprint with permission from Publisher Elsevier) COX-2 and Human Schwannomas Schwannoma is a common tumor of the…
