Cognitive disorders of the very old
Figure 25.1 Overlap in neuropathology among dementia and non-dementia cases in the 90+ Study. Corrada et al., Curr Alzheimer Res. 2012 July 1; 9(6): 709–17. (Reproduced with permission [47].) This…
Delirium masquerading as dementia
Urine analysis and cultureChest radiographElectrocardiogramFurther evaluation guided by initial evaluationBrain imaging with magnetic resonance with contrast (preferred) or computed tomographySerum ammoniaErythrocyte sedimentation rateBlood culturesLumbar puncture (if suspicion of meningitis, should…
Treatment of Alzheimer’s disease
astheniaNausea, vomiting, diarrhea, depression, headache, anxiety, application site reaction All three medications have shown efficacy through randomized, double-blind placebo-controlled trials (RCTs) with varying durations from 3 to 12 months. Compared…
Early clinical features of the parkinsonian-related dementias
7 [1–14]f4.5 [3–10]gTypical clinical featuresCognitive featureMCI: any subtype, executive dysfunction, visuospatial dysfunction, verbal blocking, misidentification errors, impaired attention, variable memory impairmentMCI-PD, executive dysfunction, visuospatial dysfunction, impaired attentionMCI-SD executive, MCI-SD language…
Non-amnestic mild cognitive impairment
Figure 16.1 Common structural neuroimaging features of non-amnestic mild cognitive impairment subtypes. Dysexecutive MCI. An 80-year-old man with hypertension, chronic tobacco use, and emphysema presented with new persistent mental rigidity…
Logopenic variant of primary progressive aphasia
Figure 13.1 Atrophy pattern in patients with lvPPA variants versus controls. This statistical parametrical mapping depicts patterns of gray matter atrophy in patients with logopenic variant compared to healthy controls…
The cognitive neurology of corticobasal degeneration and progressive supranuclear palsy
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 14 The cognitive neurology of corticobasal degeneration and progressive supranuclear palsy Carolyn A. Fredericks and Suzee E. Lee The Behavioral Neurology of Dementia, 2nd edn,…
The non-fluent/agrammatic variant of primary progressive aphasia
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 11 The non-fluent/agrammatic variant of primary progressive aphasia Murray Grossman The Behavioral Neurology of Dementia, 2nd edn, ed. Bruce Miller and Bradley Boeve. Published by…
Frontotemporal dementia
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> Chapter 9 Frontotemporal dementia Shirley Y. Pang and Bruce L. Miller The Behavioral Neurology of Dementia, 2nd edn, ed. Bruce Miller and Bradley Boeve. Published by…
Alzheimer’s disease
Figure 8.1 Protein and functional imaging in Alzheimer’s disease. (A) Pittsburgh compound B (PIB) binds to brain amyloid in a patient clinically diagnosed with Alzheimer’s disease (AD) compared with a…
