26 CHAPTER First-Generation Antiepileptic Drugs José E. Cavazos The first-generation antiepileptic drugs (AEDs), often known as traditional AEDs, marked a significant advance in epilepsy therapy. Before the introduction of phenobarbital,…
30 CHAPTER Stimulation Therapy William B. Gallentine Despite the addition of numerous new antiepileptic drugs (AEDs) over the past 20 years, a substantial number of patients with epilepsy (approximately 35%)…
1 CHAPTER Pathophysiology Cheolsu Shin The past decade has seen an explosion of the discovery of various genetic causes of many diseases, including epilepsy. With the rapid technological development in…
29 CHAPTER Newest Antiepileptic Drugs and Drugs in Development K. Nicole Mims and Aatif M. Husain Despite the approval of many new antiepileptic drugs (AEDs) in the past 20 years,…
44 CHAPTER EMU Safety Concerns Susan Hollar and Deborah LaBelle-Scarfo There are a variety of challenges, details, and protocols associated with epilepsy monitoring unit (EMU) admissions. While any inpatient admission…
42 CHAPTER Epilepsy and Sleep Erick N. Viorritto and Sujay M. Kansagra Even before the advent of EEG in the early twentieth century, clinical observation had borne out a connection…
41 CHAPTER Epilepsy and Headaches Timothy A. Collins Epilepsy and migraine have been discussed as having possible links since the late 1800s. In 1906, Gowers gave a series of lectures…
39 CHAPTER Social Issues David M. Labiner Living with epilepsy is fraught with difficulties not endured by individuals without epilepsy. Issues include the fact that individuals with epilepsy tend to…
37 CHAPTER Psychogenic Nonepileptic Events Jonathan J. Halford Nonepileptic events (NEEs) are episodes of altered movement, sensation, or experience resembling epileptic seizures which are not associated with ictal epileptiform discharges…
33 CHAPTER Alternative Therapies William L. Bell What is considered mainstream versus alternative therapies in medicine is very dependent on time and geography. The late nineteenth-century classic texts by Gowers…
