Fig. 2.1 Components of a basic test accuracy question with examples. The top row gives the terminology used. Other rows give examples of varying complexity; these include both the traditional…
Fig. 7.1 Scatter plot of the Montreal Cognitive Assessment (MoCA) and the Mini-mental State Examination (MMSE) scores for normal controls (NC) and subjects with Mild Cognitive Impairment (MCI) and mild…
Start available symptomatic medications at earliest possible stage to reduce burden of symptoms Identify patients who would best benefit from disease modifying medications as they become available Patients can participate…
ACE ACE-R ACE-III M-ACE MMSE Orientation: time 5 5 5 4 5 Orientation: place 5 5 5 5 Registration 3 3 3 3 Attention/concentration (serial 7 s, DLROW) 5…
Question 1 – What year is it? (Orientation) The exact year must be given, however an incomplete numerical value for the year (e.g. 11 instead of 2011) is accepted as…
Test (abbreviation) Reference(s) Abbreviated Mental Test Score (AMTS) Hodkinson (1972) [1] AB Cognitive Screen 135 (ABCS135) Molloy et al. (2005) [2], Standish et al. (2007) [3] Animal fluency test Sebaldt…
Compared with 10 years ago how is this person at: 1 2 3 4 5 1. Remembering things about family and friends e.g. occupations, birthdays, addresses Much improved A bit…
Reference N % dementia Sensitivity Specificity PPV NPV MC AUC Two-stage English [2, 13]a, b 246 29 0.85 0.86 0.71 0.93 14.2 % 0.89 Chinese [5]a, b 456 22 0.97…
Purpose of test Sensitivity Specificity PPV NPV Overall correct LR+ LR− CUI+ CUI− Dementia Detection of dementia vs HC 81.3 % (80.6–82.1 %) 89.1 % (88.7–89.5 %) 74.8 % (74.0–75.6…
