Toxic Neuropathies
INTRODUCTION Print Section Listen This chapter reviews neuropathies associated with various drugs and other environmental exposures (Table 20-1). Toxic neuropathies due to chemotherapeutic agents are discussed in Chapter 19. The…
Guillain–Barré Syndrome and Related Disorders
INTRODUCTION Print Section Listen Landry described a condition characterized by acute ascending paralysis in 1859. Later, Guillain, Barré, and Strohl noted the areflexia and the albuminocytologic dissociation in the cerebral…
Idiopathic Polyneuropathy
INTRODUCTION Print Section Listen In our experience and others, a cause for neuropathy will not be found in as many as 50% of cases despite an extensive work-up.1–11 The chronic…
Neuropathies Associated with Endocrinopathies
INTRODUCTION Print Section Listen Various peripheral neuropathies are associated with the different endocrinopathies (Table 21-1). In particular, peripheral neuropathy associated with diabetes mellitus (DM) is one of the most common…
Vasculitic Neuropathies
INTRODUCTION Print Section Listen Vasculitis is an immune-mediated disorder directed against blood vessels, which results in ischemia to end organs supplied by the affected blood vessels.1–5 The vasculitides can be…
Neuropathies Related to Nutritional Deficiencies
INTRODUCTION Print Section Listen Patients can develop neuropathies due to inadequate nutrition and subsequent vitamin deficiency (Table 18-1). Nutritional deficiency-related polyneuropathies are currently uncommon, especially in developed countries. However, these…
Muscle and Nerve Histopathology
INTRODUCTION Print Section Listen Muscle and nerve biopsies can be extremely useful in the evaluation of patients with myopathies and neuropathies. That said, not everyone suspected of having a muscle…
Testing in Neuromuscular Disease
INTRODUCTION Print Section Listen The role of laboratory testing in the diagnosis of neuromuscular disease is described in the first chapter. Tests are ideally used to support a clinically established…
The Rehabilitation of Neuromuscular Diseases
INTRODUTION Print Section Listen Rehabilitation is the process of assisting a person to maximize function and quality of life. Therefore, rehabilitation matters to people with neuromuscular diseases because it enables…
Amyotrophic Lateral Sclerosis
INTRODUCTION Print Section Listen The motor neuron diseases (MNDs) are categorized by their pathological affinity for the voluntary motor system including anterior horn cells, certain motor cranial nerve nuclei, and…
