Evaluation of peripheral nerve lesions
Disclosures Dr. Ly has no disclosures. Dr. Jordan has research funding from the Department of Defense, the National Institutes of Health, and the Burke Foundation. He receives royalties from Elsevier…
Evaluation of a dural-based lesion
Introduction There is significant overlap in the imaging appearance and presentation of dural-based mass lesions. The differential diagnosis includes both benign lesions (such as meningioma—WHO grade I) and more aggressive,…
Imaging of spinal lesions
Introduction Spinal cord tumors are uncommon causes of back pain, radicular pain, and sensorimotor deficits in adults and pediatric patients. Primary spinal tumors are less common than intracranial tumors and…
Evaluation of an infratentorial lesion
Introduction The posterior fossa is the infratentorial compartment of the cranial vault, which houses the cerebellum and the bulk of the brainstem. Tumors that occur in this region can arise…
Evaluation of a supratentorial parenchymal lesion
Introduction Central nervous system (CNS) tumors encompass histologically diverse entities with widely varying prognostic and therapeutic implications. Within the brain, tumors can be divided into two main categories: primary and…
Evidence-based approaches to chemotherapy for gliomas
Introduction Chemotherapy has a crucial role in the management of gliomas. Traditionally, the management is characterized by an extensive surgery followed by a combination of radiotherapy (RT) and chemotherapy. In…
Introduction to radiation therapy
Background: radiation biology and physics overview Radiation therapy treats cancer by causing DNA damage, most importantly double-strand breaks (DSBs). Although normal cells can efficiently detect and repair DSBs through homologous…
Fundamentals of neuropathology: Introduction to neuropathology and molecular diagnostics
Introduction In typical cases, the clinical workflow for brain tumors begins with imaging studies; however, despite the increased sensitivity and capabilities of these methodologies, diagnosing brain tumors requires histopathologic evaluation…
Surgical considerations for brain and spine tumors
Introduction to brain and spine tumor surgery For tumors affecting the brain and spinal cord, surgical resection is the fastest and most definitive treatment. In some cases, it is also…
Ethics and law
Decision-making capacity One of the most common ethical issues encountered in brain injury medicine centers on the circumstances in which it is permissible (or even obligatory) to restrict the freedom…
