Gait Disorders
Introduction Walking is an extraordinarily complex task requiring integration of the entire nervous system, making gait susceptible to a variety of underlying neurologic abnormalities. Gait disorders are common and contribute…
Sleep Disorders
Introduction Sleep is a universal function of living species, comprising one-third of human life. Poor quality or insufficient sleep has been associated with worsening function of most body systems, including…
Autonomic Disorders
Anatomic and Physiologic Remarks The principal role of the autonomic nervous system (ANS) is the maintenance of homeostasis by regulating and integrating the activities of essentially all organs. The ANS…
Demyelinating Disease
Introduction In 1868 Jean-Martin Charcot provided the first detailed anatomic illustrations of “la sclérose en plaques,” characteristic periventricular white matter lesions that are now appreciated as a pathologic hallmark of…
Motor Neuron Disease
Introduction Motor neuron diseases are the result of dysfunction of upper motor neurons in the precentral gyrus of the frontal lobe and/or lower motor neurons in the ventral horn of…
Approach to the Diagnosis and Management of Peripheral Neuropathy
Introduction Peripheral neuropathy is among the most common neurologic problems encountered by primary care clinicians, as it affects up to 8% of adults over the age of 55. Despite its…
Spinal Cord Disorders: Myelopathy
Introduction Myelopathy is a clinical syndrome caused by spinal cord dysfunction. Practitioners across different specialties from emergency medicine to trauma surgery, to neurology, to internal medicine encounter patients with myelopathy….