Vitamin D and spinal cord injury
Abbreviations 25(OH)D 25-hydroxyvitamin D, also known as calcidiol 1,25(OH) 2 D 1,25-dihydroxyvitamin D, also known as calcitriol IOM Institute of Medicine UVB ultraviolet B SCI spinal cord injury VDR vitamin…
Curcumin usage for inflammation and spinal cord injury
List of abbreviations AGP α1-acid glycoprotein AMPK adenosine monophosphate-activated protein kinase AQP4 aquaporin 4 BBB Basso, Beattie, Bresnahan ERKs extracellular signal-regulated kinases GFAP glial fibrillary acidic protein GSK-3β glycogen synthase…
Viral vector gene therapy approaches for regeneration and repair in spinal cord injury
List of abbreviations SCI spinal cord injury CNS central nervous system AdV adenovirus HSV herpes simplex virus LV lentivirus AAV adeno-associated virus IM intramuscular IN intraneural IV intravenous IT intrathecal…
Use of (−)-epigallocatechin-3-gallate on spinal cord injury
List of abbreviations AGEs advanced glycation end products AD Alzheimer’s disease ACR acrylamide AKT protein kinase B APP amyloid precursor protein AQP4 astrocyte expressing aquaporin-4 ARE antioxidant response element α7nAChR…
Stem cells and chronic spinal cord injury: Overview
Abbreviations ALS amyotrophic lateral sclerosis BDNF brain-derived neurotrophic factor CNS central nervous system DNA deoxyribonucleic acid EMG electromyography ESC embryonic stem cell GABA gaba-aminobutyric acid iPSC induced-pluripotent stem cell ISNCSCI…
High-intensity interval training in individuals with spinal cord injury
Abbreviations AGREE Appraisal of Guidelines, Research and Evaluation HIIT high-intensity interval training MIT moderate-intensity continuous training NSCISC National Spinal Cord Injury Statistical Center SCI spinal cord injury SIT sprint interval…
Exploring the exogenous and endogenous effects of melatonin on spinal cord injury
List of abbreviations COX cyclooxygenase GSH glutathione IL-1α interleukin-1α IL-1β interleukin-1β iNOS inducible nitric oxide synthase L/D light/dark L/L light/light LPO lipid peroxidation MDA malondialdehyde MT melatonin NF-κB nuclear factor-κB…
Mitochondrial biogenesis for the treatment of spinal cord injury
Abbreviations 5-HTR 5-hydroxytryptamine receptor 7,8-DHF dihydroxyflavone Ac acetyl group AICAR 5-aminoimidazole-4-carboxamide ribonucleotide Akt protein kinase B AMPK adenosine monophosphate-activated kinase AP-1 activating protein 1 ATP adenosine triphosphate BSCB blood–spinal cord…
Anti-repulsive guidance molecule: An antibody treatment in spinal cord injury
Abbreviations BBB blood brain barrier BMP bone morphogenetic protein CNS central nervous system CST corticospinal tract DCC deleted in colorectal cancer GPI glycosylphosphatidylinositol MCAO middle cerebral artery occlusion MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine…
GEMINI-supported spinal cord transplantation for the treatment of chronic spinal paralysis: Overview and initial clinical translation
Introduction There is at present no biological cure for chronic paralysis following spinal cord injury (SCI). A medley of experimental approaches have been tried over the years, and, despite some…
