17 Stimulation of Amygdala and Hippocampus Claudio Pollo and Jean-Guy Villemure Despite considerable advances in pharmacological therapy for epilepsy, 25 to 30% of medically treated epileptic patients continue to have…
18 Deep Brain Stimulation Casey Halpern, Uzma Samadani, Jurg L. Jaggi and Gordon Baltuch Approximately one-third of patients with epilepsy will have persistent seizures despite maximal antiepileptic drug (AED) therapy.1–3…
5 Selective Amygdalohippocampectomy Warren W. Boling It is useful to categorize temporal lobe epilepsy into one of two types based on the anatomical site of seizure onset: neocortical (lateral temporal)…
20 Radiosurgery Jean Régis, Fabrice Bartolomei and Patrick Chauvel There is growing interest in the use of radiosurgery for treating medically intractable epilepsy. Our local clinical experience (122 patients), accumulated…
4 Temporal Lobectomy and Amygdalohippocampectomy Patrick J. Connolly and Gordon H. Baltuch Layout of the Operating Room and Positioning the Patient A multidisciplinary team is required for epilepsy surgery and…
13 Callosotomy Jean-Pierre Farmer, Abdulrahman J. Sabbagh and Jeffrey D. Atkinson The goal of the majority of surgical and medical therapies for the treatment of epilepsy is the complete cessation…
12 Motor/Sensory/Language Mapping James Schuster Electrical cortical stimulation was first reported by Bartholow in 1874.1 Cushing, Penfield, Rasmussen, and others greatly refined these techniques with regard to intraoperative stimulation and…
9 Hypothalamic Hamartomas Sandeep Mittal, José Luis Montes, Jean-Pierre Farmer and Abdulrahman J. Sabbagh The term hamartoma is derived from the Greek word hamartion meaning bodily defect. A hamartoma is…
14 Anatomical Hemispherectomy Gregory G. Heuer and Phillip B. Storm The general principle of surgery for intractable epilepsy is the removal or isolation of the region of brain that is…
10 Multiple Subpial Transections Albert E. Telfeian The initiation and propagation of epileptiform discharges in the brain divides the problem of focal epilepsy into two parts: one, the generation of…
