ALZHEIMER’S DISEASE
CHAPTER 65 ALZHEIMER’S DISEASE John G.F. Boughey, Neill R. Graff-Radford DEFINITION Alzheimer’s disease is a progressive degenerative brain disease defined by both a clinical component and a pathological component: 1….
SPINE AND SPINAL CORD: DEVELOPMENTAL DISORDERS
CHAPTER 38 SPINE AND SPINAL CORD: DEVELOPMENTAL DISORDERS Valerie S. Tay, Andrew Kornberg, Mark Cook Developmental disorders of the spine and spinal cord occur because of defects in the development…
DEMENTIA WITH LEWY BODIES
CHAPTER 70 DEMENTIA WITH LEWY BODIES Bradley F. Boeve HISTORICAL PERSPECTIVE Okazaki and colleagues first described Lewy bodies in the cerebral cortex in patients with dementia in 1961.1 Few reports…
INVESTIGATIONS IN MULTIPLE SCLEROSIS
CHAPTER 77 INVESTIGATIONS IN MULTIPLE SCLEROSIS Robert Brenner Investigations in the setting of multiple sclerosis have three main roles: to help support or refute the diagnosis, to provide insights into…
ISCHEMIC STROKE: MECHANISMS, EVALUATION, AND TREATMENT
CHAPTER 42 ISCHEMIC STROKE: MECHANISMS, EVALUATION, AND TREATMENT Bernardo Liberato, John W. Krakauer Stroke is a major public health problem. An estimated 500,000 new and 200,000 recurrent strokes occur in…
VESTIBULAR SYSTEM DISORDERS
CHAPTER 27 VESTIBULAR SYSTEM DISORDERS Linda M. Luxon, Doris-Eva Bamiou Humans have developed a sophisticated and complex mechanism for maintaining balance that relies on the integration and modulation of sensory…
NEUROLOGICAL COMPLICATIONS OF CANCER TREATMENTS
CHAPTER 100 NEUROLOGICAL COMPLICATIONS OF CANCER TREATMENTS William Whiteley, Robin Grant People with cancer frequently develop neurological symptoms. One of the dilemmas facing doctors is whether these symptoms are directly…
INFLAMMATORY MYOPATHIES
CHAPTER 89 INFLAMMATORY MYOPATHIES Mohammad Salajegheh, Marinos C. Dalakas The inflammatory myopathies are a heterogeneous group of acquired diseases of skeletal muscle. They have in common the presence of varying…
VITAMIN DEFICIENCIES AND OTHER NUTRITIONAL DISORDERS OF THE NERVOUS SYSTEM
CHAPTER 109 VITAMIN DEFICIENCIES AND OTHER NUTRITIONAL DISORDERS OF THE NERVOUS SYSTEM Laurence J. Kinsella A vitamin is a substance that serves as a cofactor for a biochemical reaction and…
