Biomechanics of the Healthy and Diseased Spine
4 Biomechanics of the Healthy and Diseased Spine Hans-Joachim Wilke and Fabio Galbusera Abstract The intervertebral disc (IVD) is a pad of soft tissue that uniformly distributes the stresses due to…
Grading Scales for Disc Degeneration and Regeneration: Clinical and Experimental
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Regulatory Overview: Obtaining Regulatory Approval of a Biological/Cell Product
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What Will the Future Bring? Perspectives From Around the World
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What Makes Biological Treatment Strategies and Tissue Engineering for DDD Interesting to Industry?
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Biological Treatment Approaches: Basic Ideas and Principles
9 Biological Treatment Approaches: Basic Ideas and Principles Victor Y. Leung and Kenneth M.C. Cheung Abstract Clinical studies indicate an association of intervertebral disc (IVD) degeneration severity with low back pain,…
Trial Designs to Establish Efficacy and Safety in Multimodal Therapies
5Trial Designs to Establish Efficacy and Safety in Multimodal Therapies Highlights Developing and evaluating multimodal strategies to treat complex diseases will require innovative strategies and the involvement of multiple stakeholders…
Exploring the State of the Science
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Role of Research Funders in Multimodal Therapy Development
7Role of Research Funders in Multimodal Therapy Development Highlights Government and charitable funding agencies can play an important role in filling the gaps that may exist in the development of…
Multimodal Therapy: Overview of Principles, Barriers, and Opportunities
2Multimodal Therapy: Overview of Principles, Barriers, and Opportunities Multimodal therapies are intended to optimize treatment of brain disorders by delivering different types of therapy together. The multiple modes used may…
