Primary Incidence (%) Breast 13–22 Lung 15–19 Prostate 10–18 Lymphoma 8–10 Sarcoma 7.5–9 Kidney 6–7 Gastrointestinal 4–5 Melanoma 2–4 Myeloma 4.5–5 Unknown 4–11 Pathogenesis and Pathophysiology Batson, through his cadaveric…
Fig. 19.1 Glucocorticoid mechanisms of action. Mechanisms of glucocorticoid (GC) action. GC crosses the cell membrane and binds to the glucocorticoid receptor (GR) in the cytoplasm. GRs are kept in an…
Fig. 24.1 A 73-year-old man with an 18-month history of esophageal adenocarcinoma presented in April 2013 with right hemiparesis. a (postcontrast T1 MRI) reveals a mass that preoperatively was felt to…
© Springer International Publishing AG 2018David Schiff, Isabel Arrillaga and Patrick Y. Wen (eds.)Cancer Neurology in Clinical Practicehttps://doi.org/10.1007/978-3-319-57901-6_34 34. Neurological Complications of Cancer and Cancer Therapies in Long-Term Survivors Isabel Arrillaga1 (1) Department of Neurology/Neuro-Oncology, Massachusetts General…
Fig. 12.1 Multifactorial etiology of cognitive dysfunction in cancer patients As disruption in neurocognitive function can be a major cause of impaired quality of life, attention to these symptoms and consideration…
Fig. 27.1 A 34-year-old man presented with left-sided headaches, word finding difficulty, and short-term memory loss. Contrast-enhanced T1 coronal MRI (A) demonstrates a heterogeneously enhancing mass that appears to extend to…
Fig. 17.1 Ipilimumab-related hypophysitis. MRI of the brain in a 77-year-old woman with metastatic melanoma. After the fourth cycle of ipilimumab, she developed profound weakness, fatigue, and confusion, with significant endocrine…
l-Asparaginase Chlorambucil Interferon-a Bevacuzimab Cyclosporin A Lomustine Carmustine Etoposide Methotrexate Cisplatin 5-Fluorouracil Procarbazine Busulphan Ifosfamide Vincristine Table 9.2 Semiology and aetiology of new-onset seizures in cancer Semiology Aetiological condition Isolated generalized…
Clinical history suggesting a brain tumor headache Cancer patient with a new headache or a change in headache pattern Unrelenting crescendo headache Headache resistant to all medical interventions Pain location…
Number of patients Percentage of consults Chief complaint Back pain 385 18 Headache 192 9 Other pain 160 7 Altered mental status 521 24 Weakness 395 18 Sensory deficit…
