Antithrombotics: Antiplatelet Drugs
Fig. 28.1 Mechanisms of antiplatelet drugs 28.1 Antiplatelet Therapy of Acute Ischemic Stroke and TIA 28.1.1 Aspirin vs. Placebo In the International Stroke Trial (IST), patients received aspirin 300 mg…
History of Intra-arterial Thrombolysis
Fig. 7.1 The history of thrombolysis. Prolyse in Acute Cerebral Thromboembolism (PROACT) II trial; The Mechanical Embolus Removal in Cerebral Ischemia (MERCI); Interventional Management of Stroke [IMS] III; Local Versus…
Stroke Center
Patient care elements Acute stroke team Written care protocols Emergency medical services Emergency department Stroke unit Neurosurgical services Imaging services: brain, cerebral vasculature, cardiac Laboratory services Rehabilitation services Administrative/support elements…
Stroke Unit
Fig. 2.1 Stroke unit. Interior view of stroke unit (a); exterior (b) and interior (c) view of mobile stroke unit. Reproduced by permission of Business Wire (University of Tennessee Web…
Intravenous Thrombolysis for Acute Ischemic Stroke
Fig. 6.1 History of clinical trials of IV thrombolysis Finally, following the publication of the ECASS-III study in 2008, the time window for administration of intravenous (IV) thrombolysis was expanded…
Overview of Patient Management Flow
Fig. 4.1 A schematic diagram showing patient management flow (CT computed tomography, MRI magnetic resonance imaging, IV intravenous, IA intra-arterial) 4.1 Care in the Emergency Unit Treatment of suspected stroke…
Use of Advanced Neuroimaging (fMRI, DTI/Tractography) in the Treatment of Malignant Gliomas
Fig. 1.1 Hand motor fMRI activation in a patient with two contrast enhancing tumors that both displace the motor gyrus and efface the central sulcus. The red line indicates the position…
Fluorescence-Guided Resection of Malignant Gliomas
Fig. 6.1 Scheme illustrating the nature of fluorescence and how it is visualized A Brief History Historically, the use of a fluorophore for highlighting malignant glioma tissue was first described by…
The Role of Laser-Induced Thermal Therapy in the Management of Malignant Gliomas
Fig. 7.1 MRI-compatible surgical suite at Yale New Haven Hospital. Patient positioning and preparation prior to obtaining pre-LITT MRI. Heat delivery is performed under MRI guidance for intra-procedural monitoring and confirmation…
The Usefulness of Stereotactic Neuronavigation Along with Intraoperative Imaging in Malignant Brain Tumor Surgery
Fig. 4.1 Intraoperative use of ultrasound revealing a hyperechoic lesion representing tumor prior to resection. A hypoechoic area in the center is the carotid artery. The apparatus remains on the field…
