iPS Cells and iN Cells
Fig. 4.1 Summary of induction of iPSCs, iNSCs, and iNCs and direct in vivo reprogramming (Modified from Yamashita et al. [28]). (a) Overexpression of Oct3/4, Sox2, Klf4, and c-Myc can…
Bone Marrow-Derived Mononuclear Cells
Fig. 1.1 Overview of the proposed mechanisms of bone marrow-derived mononuclear cell (MNC)-based stroke therapies. Cells transplanted by intravenous (IV) or intra-arterial (IA) injection migrate toward the ischemic boundary zone…
Cell Therapy for Ischemic Stroke with Bone Marrow Stromal Cells
© Springer Japan KK 2017Kiyohiro Houkin, Koji Abe and Satoshi Kuroda (eds.)Cell Therapy Against Cerebral Stroke10.1007/978-4-431-56059-3_2 2. Cell Therapy for Ischemic Stroke with Bone Marrow Stromal Cells Satoshi Kuroda1, 2 , Hideo Shichinohe2 and Kiyohiro Houkin2 (1) Department of Neurosurgery,…
Route, Cell Dose, and Timing
Fig. 6.1 Schematic drawing of the transplantation route with its advantage and disadvantage 6.2.1 Intravenous Route One of the major advantages of using intravenous route for cell transplantation is its…
Cell Culture
Author Year Conditions being studied Study type Cell transplantation procedures Stroke type Timing of delivery after stroke Phase category Location Cell type Cell source Delivery route Kondziolka et al. 2000…
Neuroradiology
, Mark Gorman2 and Salman Al Jerdi2 (1) Department of Cardiovascular Medicine and Electrophysiology, Yale School of Medicine, Yale-New Haven Hospital, New Haven, CT, USA (2) Department of Cardiovascular Medicine, Yale School of…
Intracranial Hemorrhage
Figure 13-1 Hypertensive hemorrhage: A 47-year-old male with hypertensive urgency – large, acute hematoma in the right basal ganglia with mild perilesional edema causing mass effect, midline shift, and subfalcine…
Vascular Malformations
Figure 14-1 Hemorrhage due to AVM. Initial noncontrast CT (a) shows left temporal lobar hematoma with overlying subdural hemorrhage. CTA (b) shows a parenchymal nidus seen as a prominent tuft…
Clinical Cardiology
Atrial fibrillation Mechanical prosthetic valve Left atrial appendage thrombus Left ventricular thrombus Anterior wall MI Endocarditis Aortic sclerosis Dilated cardiomyopathy PFO /atrial septal aneurysm Atrial flutter Mitral stenosis Aortic dissection…
Classification of Stroke
Figure 7-1 Reversible cerberal vasoconstriction syndrome. A 58-year-old female that presented with acute severe headache and vision changes. Axial FLAIR image (a) shows T2 hyperintense lesions in the bilateral parieto-occipital…
