© Springer International Publishing Switzerland 2017Gin S. Malhi, Marc Masson and Frank Bellivier (eds.)The Science and Practice of Lithium Therapy10.1007/978-3-319-45923-3_4 4. The Effect of Lithium on Gene Expression Modulation Alessio Squassina1, 2 , Claudia Pisanu1 and Martin Alda2 (1) Department…
© Springer International Publishing Switzerland 2017Gin S. Malhi, Marc Masson and Frank Bellivier (eds.)The Science and Practice of Lithium Therapy10.1007/978-3-319-45923-3_8 8. Lithium Response Variability (Pharmacogenomics Studies) Alexandre Dayer1 , Nader Perroud2 and Jean-Michel Aubry3 (1) Mood Disorders Unit, Division of…
Fig. 10.1 Timeline of key figures in relation to lithium (From Malhi and Gershon 2009) 10.5 Summary The 1950s was a prodigious decade for modern psychopharmacology. The principal efficient molecules…
© Springer International Publishing Switzerland 2017Gin S. Malhi, Marc Masson and Frank Bellivier (eds.)The Science and Practice of Lithium Therapy10.1007/978-3-319-45923-3_5 5. Neuroimaging and Lithium Josselin Houenou1, 2, 3, 4 , Chloé Benizri2, 3 and Barbara Jakubowicz2, 3, 4 (1) AP-HP,…
Study population No of subjects Type of XR Li Reference Observed pharmacokinetics parameters Normal control subjects 6 Lithium carbonate LP 400 mg (after 12 h) Hunter (1988) C max =…
Organ system Frequent symptoms Heart Chest pains, paroxysmal tachycardias Blood pressure Hypertension and hypotension regulation disorders, syncope Upper gastrointestinal tract Nausea, feeling of repletion, meteorism Lower gastrointestinal tract Pain, diarrhoea,…
Behaviour Feelings Body Thoughts Avoidance, flight Feelings of tension, worry, panic, unreality, fear of going crazy, of dying, of losing control Trembling, sweating, heart pounding, light-headedness, dizziness, muscle tension, nausea,…
Transferring patient-centered interview Let the patient finish talking Use open-ended questions Pause Encourage the patient to continue talking Paraphrase Summarize the contents Reflect the patient’s emotions Let the Patient Finish…
What do you think the patient was feeling at that moment? What kind of person is the patient? What do you know about his/her life situation, his present family, and…
Fig. 7.1 Genogram The proposal to create a genogram can be introduced by the doctor in the following way: “We have talked in detail about your problem. Now I would…
