Table 26.2 Genetic Etiologies of Malformations of Cortical Development MALFORMATIONS OF CORTICAL DEVELOPMENT Accurate diagnosis of MCD relies primarily on recognition of the malformation on brain MRI, which, in turn,…
Figure 25.1. Dorsolateral FLE with seizures arising from the motor strip: a 21-year-old woman with simple partial seizures since a viral illness at age 9. Seizures began to cluster at…
aAfter administration of eslicarbazepine acetate. CYP, Cytochrome P450; UGT, UDP-glucuronosyltransferase; NAT, N-acetyltransferase; nk, not known. Figure 44.1. Relationship between pharmacokinetics and pharmacodynamics. PHARMACOKINETIC PARAMETERS Absorption Absorption refers to the passage…
Figure 85.1. Proposed algorithm for the evaluation of patients with multilobar and multilesional epilepsy. The algorithm departs from the findings in the brain MRI. The first element to consider is…
Figure 62.1. Rufinamide. MW 238.2, (C10H8F2N4O). Rufinamide is nearly insoluble in water and slightly soluble in methanol and ethanol. This would make it difficult to prepare an intravenous formulation. Solubility…
Figure 19.1. EEG–EMG recording with surface electrodes in a 3-year-old boy with MAE (Doose syndrome). Three brief and symmetric myoclonic jerks each time-locked to single generalized single spike–wave discharges are…
Table 27.2 Tumor Types Encountered in Medically Intractable, Chronic Epilepsy using Data Retrieved from the European Epilepsy Brain Bank Table 27.3 Seizure Frequency in Various Brain Tumor Types CLINICAL CHARACTERISTICS…
