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Figure 55.1. Chemical structure of gabapentin, pregabalin, and gabapentin enacarbil. The mechanism of action of gabapentinoids differs from that of other antiepileptic drugs (AEDs). Contrary to initial belief, they do…
For an up-to-date review of an individual metabolic disease or to find a lab where an analyte or gene test can be sent, we recommend visiting the NIH GeneReviews site…
Figure 59.1. 2-(2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl) benzonitrile hydrate, M.W. 349.38 (perampanel). PERAMPANEL PHARMACOLOGY Glutamate is the major excitatory neurotransmitter in the CNS. Fast glutaminergic transmission is mediated predominantly by NMDA and AMPA receptors…
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Figure 58.1. The chemical structure of LEV. MECHANISM OF ACTION Prior to undergoing standardized AED testing by the National Institutes of Health, LEV was found to have antiepileptic properties. In…
The following overview of nonepileptic paroxysmal disorders is organized by age, type, and time of occurrence. Psychogenic nonepileptic seizures are discussed in Chapter 40. INFANCY Sleep During infancy, at least…
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Related posts: The Natural History of Seizures Hormones, Catamenial Epilepsy, Sexual Function, and Reproductive and Bone Health in Epilepsy Gabapentin and Pregabalin Sleep and Epilepsy Outcome and Complications of Epilepsy…
