Fig. 22.1 Electroporation (a) By application of brief electric pulses it is possible to transiently permeabilise the cell membrane (electroporation). This allows free passage of molecules to the cell cytosol…
Lesion Overall endocrinopathy Diabetes insipidus Panhypopituitarism Craniopharyngioma 56–83 % 4–37 % 24–42 % Rathke’s cleft cyst 66–70 % 0–13 % 0–11 % Arachnoid cyst 50–60 % Case reports Case reports…
No Significant hemorrhage Other complications Subsequent microsurgical excision Subsequent adjunctive therapies High grades gliomas VL 1 1 1 3rd V 4 1 3 Low grades gliomas VL 2 2 …
Fig. 30.1 An example of a cerebellar metastasis treated with 18 Gy in a single fraction, and the 18 Gy isodose line in yellow conforms around the target. Despite a…
Fig. 18.1 Case 1 (a–f): Preoperative axial (a), coronal (b) and sagittal (c) T1 weighted contrast MRI showing a giant adenoma with moderate suprasellar extension and almost complete filling of…
Fig. 24.1 General schematic of cellular GSH biosynthesis, utilization, export, and salvage. Glutathione (GSH) biosynthesis requires two ATP-dependent reactions: the glutamate cysteine ligase (GCL)-mediated formation of γ-glutamylcysteine (γGC) from glutamate…
Fig. 5.1 Electron microscopy analysis. Mature adipocyte has thin cytoplasm and a nucleus characteristically squeezed by the large lipid vacuoles. The cytoplasmatic organelles are poorly represented. Scale bar = 4 μm To…
Fig. 13.1 2D [1H,1H] HRMAS spectra from controls (left) and GBM (right) tumor biopsies, acquired with a 600 MHz (1H) NMR spectrometer at an MAS rate of 3 kHz and…
Fig. 26.1 66-year old patient with the history of colorectal cancer who presented with vertigo and dysarthry. (a) native CT shows a dense mass in the right cerebellar hemisphere with…
Fig. 2.1 Schematic representation of adult rodent neurogenesis. (a) Illustration of a sagittal section through the mouse brain showing location of neurogenic zones: the subgranular zone (SGZ) of the dentate…
