Figure 22.1 Antibodies to intracellular and cell-membrane antigens in patients with limbic encephalitis. (A) Sagittal section of rat hippocampus immunolabeled with anti-Hu antibodies. (B, C) Consecutive sections of hippocampus immunolabeled…
Figure 27.1 Overnight oximetry studies in three patients with suspected sleep disordered breathing. For each example, the top tracing shows the oxygen saturation readings associated with values on the left…
2. Impaired single-word comprehensionAt least three of the following other diagnostic features must be present:1. Impaired object knowledge, particularly for low-frequency or low-familiarity items2. Surface dyslexia or dysgraphia3. Spared repetition4….
Figure 23.1 McKee’s four stages of CTE tau pathology and associated clinical features. The left column depicts 50 μm coronal tissue sections with CP-13 immunostain which labels phosphorylated tau with…
Figure 21.1 Typical brain MRI in a patient with sJCD. FLAIR (top row), DWI (middle row), and ADC map (bottom row) sequences show the typical T2-weighted hyperintensities with corresponding restricted…
Figure 18.1 Lewy-related pathology (LRP). Lewy body inclusion (arrow) in a pigmented neuron of the substantia nigra (A, hematoxylin and eosin). Immunohistochemical staining of Lewy body inclusions (arrow heads) and…
Figure 15.1 Algorithm for the diagnosis of mild cognitive impairment. To illustrate diagnosis according to Figure 15.1: an initial clinical and cognitive evaluation may show that the patient has experienced…
Figure 10.1 Atrophy maps in PPA subtypes [7, 11]. Only the left hemisphere is shown. Areas in red and yellow show peak atrophy sites when patient groups of a given…
Figure 25.1 Overlap in neuropathology among dementia and non-dementia cases in the 90+ Study. Corrada et al., Curr Alzheimer Res. 2012 July 1; 9(6): 709–17. (Reproduced with permission [47].) This…
Urine analysis and cultureChest radiographElectrocardiogramFurther evaluation guided by initial evaluationBrain imaging with magnetic resonance with contrast (preferred) or computed tomographySerum ammoniaErythrocyte sedimentation rateBlood culturesLumbar puncture (if suspicion of meningitis, should…
