Fig. 3.1 Validation of the neuronal origin of serotonin (5-HT) sampled by a microdialysis probe (exposed tip length, 1 mM) in the central nucleus of the amygdala (CeA) of freely…
Fig. 26.1 Brain perfusion SPECT in a normal dog (horizontal/transverse slices). The colour scale gives information on the intensity of radioactivity registered in different areas: highest uptake is related with…
, Nozipho Nyakale1 and Mike Sathekge1 (1) Nuclear Medicine Department, Steve Biko Academic Hospital, University of Pretoria, Voortrekkers Road and Malan Street, Capital Park, Pretoria, South Africa Mike Sathekge Email: mike.sathekge@up.ac.za…
Study Imaging technique employed Target Number of patients/controls Patients receiving treatment/total number of patients Results Sudo et al. (1998) PET 11C-MPB ACh 11/21 0/11 No change Derry et al. (2006)…
Fig. 16.1 The study-specific general linear model as created in SPM Intermezzo: The Study’s General Linear Model The water-activation-PET data was analysed in an imaging-specific data-analysis program called Statistical Parametric…
For a diagnosis of Apathy the patient should fulfil the criteria (A), (B), (C) and (D) (A) Loss of or diminished motivation in comparison to the patient’s previous level of…
Fig. 17.1 A schematic of the similar metabolic pathways of the 5-HT precursor tryptophan and the analogous radioisotope α-[11C]MTrp. PNS peripheral nervous system, CNS central nervous system, BBB blood-brain barrier,…
Fig. 22.1 Schematic illustration showing the major co-morbidities associated with adult attention deficit hyperactivity disorder, including alcohol and drug dependence (From Kessler et al. (2006)) 22.2 SPECT/PET Studies in Addiction…
Fig. 14.1 The amygdalocentric neurocircuitry model of posttraumatic stress disorder. Excitatory connections are labelled “+”; inhibitory connections are labelled “–” (From Deckersbach et al. (2006); adapted from Rauch et al….
Fig. 4.1 Cross section of a brain capillary, depicting the main components An important component in the protection of the brain against toxic influences is the multispecific efflux pump P-glycoprotein….
