html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 14 White matter neurobiology and cognitive dysfunction in major depressive disorder Geoffrey Chern-Yee Tan and Kang Sim Introduction Major depressive disorder (MDD) is an affective disorder…
Figure 6.1 The impact of depression on cold cognitive function. Pooled, weighted Cohen’s d effect sizes reflecting the performance of currently depressed patients (black bars) and remitted depressed patients (gray…
Figure 13.1 A simplified diagram depicting the HPA axis and its feedback mechanism. Glucocorticoids, principally cortisol in humans, influence the expression of genes comprising approximately a fifth of the genome…
Figure 11.1 Neuropsychological model of depression. Adapted from Roiser et al. (2012), with permission. Cognitive deficits and the role of antidepressant treatment A review of antidepressant treatment effects on cognitive…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 10 Implications of cognitive impairments on functional outcomes in major depressive disorder Tracy L. Greer and Cassandra R. Hatt Introduction Impaired cognitive functioning is one of…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 9 Are cognitive deficits in major depressive disorder progressive? Marie Laure Cléry-Melin and Philip Gorwood Major depressive disorder (MDD) primarily involves mood disturbances, but its association…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 8 The role of social cognition in major depressive disorder Bernhard T. Baune and Michael Weightman Introduction Correctly interpreting social information is a crucial part of…
Figure 7.1 SENSO framework showing biological, cognitive, neural, and behavioral responses following social rejection or threat of rejection. Legend: SAM: sympathetic adrenal medullary; vACC: ventral anterior cingulate; DMN: default mode…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 5 Neuroanatomy of cognition in major depressive disorder Guy M. Goodwin Cognition is defined as the mental mechanisms through which thought, experience, and sensory organs operate…
Fig. 1 Changes over the years of the MEDLINE compliance/adherence citation ratio in studies on schizophrenia Given the differences characterising the two labels, research on medication-taking behaviour should state whether a…
