Disorders of the Spinal Cord
22 Disorders of the Spinal Cord The central nervous system (CNS) comprises the brain and the spinal cord. The spinal cord plays a particularly important role in relaying…
Demyelinating Diseases of the Central Nervous System
20 Demyelinating Diseases of the Central Nervous System MULTIPLE SCLEROSIS Demyelinating diseases of the central nervous system (CNS) are characterized pathologically by an acquired loss of myelin with…
Aphasia and Other Disorders of Higher Cortical Function
PART III NEUROLOGIC DISORDERS 11 Aphasia and Other Disorders of Higher Cortical Function The behavioral neurology syndromes, including the aphasias, are some of the most interesting clinical syndromes to both…
The Approach to Weakness
5 The Approach to Weakness Weakness is one of the most common presenting neurologic complaints. Many patients may tolerate some degree of numbness, tingling, or even pain, but…
Disorders of the Neuromuscular Junction and Skeletal Muscle
24 Disorders of the Neuromuscular Junction and Skeletal Muscle Disorders of the neuromuscular junction and muscle are pure motor phenomena. The underlying pathophysiology can result in distinctive patterns…
Central Nervous System Tumors
19 Central Nervous System Tumors The most common tumors in the central nervous system (CNS) are metastases from distant neoplasms, with lung cancer accounting for nearly half of…
Movement Disorders
16 Movement Disorders PARKINSON DISEASE Idiopathic Parkinson disease (PD) is the most common neurodegenerative movement disorder and is the most important form of parkinsonism, the clinical syndrome characterized…
Neuro-Ophthalmology
4 Neuro-Ophthalmology Neuro-ophthalmology is a field that helps elucidate the causes of visual symptoms, such as double vision (diplopia), and signs including pupillary dysfunction and eye movement abnormalities….
Radiculopathy, Plexopathy, and Peripheral Neuropathy
23 Radiculopathy, Plexopathy, and Peripheral Neuropathy The peripheral nervous system (PNS) consists of spinal nerve roots, the brachial and lumbosacral plexi, peripheral nerves, autonomic ganglia, the neuromuscular junction,…
Systemic Conditions with Neurologic Manifestations
18 Systemic Conditions with Neurologic Manifestations Central and peripheral neurologic dysfunction can arise in the setting of conditions with primary endocrine, electrolyte, hematologic, or metabolic causes. Nutritional and…
