Neupsy Key

Fig. 42.1 PGP9.5 immunostaining shows normal cutaneous innervation with many intraepidermal nerve fibers (arrows) present at the unaffected right proximal thigh (a), but no intraepidermal nerve fibers are seen at…

Fig. 40.1 PGP9.5 immunostaining of skin biopsy sections shows reduced intraepidermal nerve fiber densities at the left distal leg (a), distal thigh (b) and proximal thigh (c) with no distal-to-proximal…

Fig. 38.1 (a), Intravascular lymphoma in an endomyseal blood vessel (arrow). Tumor cells distend the vascular lumen, have large nuclei and prominent nucleoli; these features are typical of a large…

Fig. 37.1 H&E stain (a) shows nerve infiltration by abundant tumor cells (arrows). The tumor cells have large nuclei and prominent nucleoli; these features are typical of a large cell…

Fig. 36.1 Nerve biopsy , leprous neuropathy. (a), An H&E-stained paraffin section of the superficial radial nerve biopsy, demonstrating a well-formed granuloma (arrow). (b), Fite stained longitudinally oriented paraffin section,…

Fig. 35.1 Hematoxylin and eosin stain (HE) of the sural nerve biopsy section shows chronic mononuclear inflammatory cells infiltrating perineurium and surrounding epineurial and endoneurial blood vessels. There is irregular…

Fig. 34.1 Sural nerve biopsy. Plastic toluidine blue stained semi-thin sections at a lower magnification (a) and a higher magnification (b) show a minimally reduced density of myelinated fibers with…

Fig. 33.1 Amyloid neuropathy. (a) Toluidine blue stained resin embedded plastic section of the biopsied nerve shows an end stage nerve with severe depletion of myelinated axons. (b) Congo red…