Neupsy Key

Fig. 19.1 Hydroxychloroquine myopathy. (a), Hematoxylin and eosin stain (HE) shows many scattered severely atrophic fibers , which are basophilic and contain sarcoplasmic vacuoles (arrows). Gomori trichrome stain (GT) shows…

Fig. 20.1 Calciphylaxis. (a), A picture of the patient’s back shows a large area of skin eschar (arrows). (b), Muscle biopsy with HE stain shows calcification of media tunica and…

Fig. 18.1 Hematoxylin and eosin stain (HE) shows a rare atrophic fiber (arrow) Final Diagnosis Mild Toxic Myopathy Induced by Statin Use Patient Follow-up The diagnosis of a mild toxic…

Fig. 16.1 HE stain shows increased internalized nuclei, a few necrotic fibers and myophagocytosis (a, arrows), and several fibers containing blue-rimmed sarcoplasmic vacuoles (b, arrows). Acid phosphatase stain shows a…

Fig. 14.1 Lipid storage myopathy. (a), HE stain shows many fibers containing multiple small sarcoplasmic vacuoles . Gomori trichrome stain (GT) shows these vacuoles are not red rimmed; a few…

Fig. 11.1 Quadriceps muscle biopsy shows mild chronic active myopathy . (a), Chronic features include marked fiber size variation, split fibers (black arrows) and frequent internalized nuclei (white arrows). (b),…

Fig. 10.1 Necrotizing granulomatous fasciitis and myositis with the presence of AFB positive micro-organisms. Muscle cross sections with hematoxylin and eosin (HE) and acid fact bacilli (AFB) stains show necrotizing…

Fig. 9.1 H&E stain (a and b) shows transmural inflammation involving several perimysial blood vessels (arrows), destruction of blood vessel walls with deposition of fibrinoid material (asterisks), and occlusion of…

Fig. 8.1 Non-caseating granulomatous myositis . Muscle cross sections stained with hematoxylin & eosin (HE) show several endomysial and perimysial granulomas (red arrows) consisting of multinucleated giant cells (green arrow)…