Knowledge and Culture
(1) Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract This chapter presents the abstract philosophical principles behind the methods presented in prior chapters. The…
Machine Learning Methods with Applications to Diagnosis
(1) Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract This chapter extends probabilistic analytical methods introduced in Chap. 2. The principle of transformation of…
Toyota Production System
(1) Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract This chapter introduces the reader to lean manufacturing principles. The life and work of W….
Process Driven Methods in Diagnosis and Treatment
(1) Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract This chapter explores processes for establishing diagnosis and guiding treatment in a dependable manner. It…
Reliance Implementation Methods Applied to a Kaizen Project
(1) Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract Reliance industries limited (RIL) owns and operates the world’s largest Greenfield oil refinery complex in…
Failure Modes and Effects Analysis
(1) Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract This chapter extends the principles of failure modes and effects analysis (FMEA) introduced in Chap….
Instrument of Brain Stimulation
Fig. 5.1 Extrel type DBS system. (a) External transmitter (model 3523). (b) Antenna. (c) Receiver (model 3360). (d) Stimulation electrode (Reprinted with the permission of Medtronic, Inc. © 1991) Fig….
Deep Brain Stimulation for Dystonia
Primary dystonia Typically early-onset: generalized DYT1 generalized dystonia Non-DYT1 generalized dystonia Paroxysmal dystonia and dyskinesias Dopa-responsive dystonia Myoclonic dystonia Rapid-onset dystonia-parkinsonism X-linked dystonia-parkinsonism Typically adult-onset: focal Blephalospasm Cervical dystonia Writer’s…
Stimulation of Globus Pallidus
Fig. 8.1 Schematic diagram of the basal ganglia–thalamocortical circuitry under normal conditions (a) and in Parkinson’s disease (b). In Parkinson’s disease, decreased excitatory inputs from the substantia nigra compacta (SNc)…
Spinal Cord Stimulation for Intractable Pain
Fig. 12.1 (a) (surface histogram) The depression of RIII (“nociceptive”) flexion reflexes induced by SCS in a 35-year-old woman with electrodes at T10 level. Each trace is the rectified average…
