Patient Selection The minimally invasive approach for aneurysms means small and strategically placed craniotomies ( â–¶ Fig. 5.1), avoiding brain retraction and minimizing tissue damage during dissection. Acceptable minimally invasive…
Anatomical Features and Patient Selection The posterior inferior cerebellar artery (PICA) has a highly variable origin: in 90% of individuals, it originates from the so-called intradural V4 segment of the…
Operating Microscope The microscope serves two main functions—magnification and illumination—permitting smaller exposures, improved visibility for dissection of delicate tissues, and safer hemostasis when working through narrow and deep surgical corridors….
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8 5-Aminolevulinic Acid and Indocyanine Green: Fluorescence-Guided Resection of Spinal Cord Intramedullary Tumors Toshiki Endo, Tomoo Inoue, and Teiji Tominaga AbstractDuring surgery for intramedullary spinal cord tumors, it is important…
16 Fluorescence-Guided Surgery, Intraoperative Imaging, and Brain Mapping (iMRI, DTI, and Cortical Mapping) Jan Coburger and Philippe Schucht AbstractIntraoperative MRI (iMRI) and intraoperative mapping/monitoring (IOM) have synergistic effects on fluorescence-guided…
12 Second Window Indocyanine Green: Near-Infrared Optical Contrast for Intraoperative Identification of Brain Tumors Ryan D. Zeh, Ryan D. Salinas, Sunil Singhal, and John Y.K. Lee AbstractWhile indocyanine green (ICG),…
18 Indocyanine Green and Cerebral Aneurysms David Bervini and Andreas Raabe AbstractWhen performing aneurysm clipping, the surgeon has to ensure that the aneurysm is completely obliterated and the parent, branching,…
13 Cancer-Targeted Alkylphosphocholine Analogs for Intraoperative Visualization Ray R. Zhang, Paul A. Clark, Jamey P. Weichert, and John S. Kuo AbstractWithin the last decade, several clinical trials pairing targeted fluorophores…
14 Tozuleristide Fluorescence-Guided Surgery of Brain Tumors Harish Babu, Dennis M. Miller, Julia E. Parrish-Novak, David Scott Kittle, Pramod Butte, and Adam N. Mamelak AbstractTozuleristide is a near-infrared (NIR) tumor-targeting…
