Stem cells and chronic spinal cord injury: Overview

Nov 9, 2024 by in NEUROLOGY Comments Off on Stem cells and chronic spinal cord injury: Overview

Abbreviations ALS amyotrophic lateral sclerosis BDNF brain-derived neurotrophic factor CNS central nervous system DNA deoxyribonucleic acid EMG electromyography ESC embryonic stem cell GABA gaba-aminobutyric acid iPSC induced-pluripotent stem cell ISNCSCI…

read more

Mitochondrial biogenesis for the treatment of spinal cord injury

Nov 9, 2024 by in NEUROLOGY Comments Off on Mitochondrial biogenesis for the treatment of spinal cord injury

Abbreviations 5-HTR 5-hydroxytryptamine receptor 7,8-DHF dihydroxyflavone Ac acetyl group AICAR 5-aminoimidazole-4-carboxamide ribonucleotide Akt protein kinase B AMPK adenosine monophosphate-activated kinase AP-1 activating protein 1 ATP adenosine triphosphate BSCB blood–spinal cord…

read more

GEMINI-supported spinal cord transplantation for the treatment of chronic spinal paralysis: Overview and initial clinical translation

Nov 9, 2024 by in NEUROLOGY Comments Off on GEMINI-supported spinal cord transplantation for the treatment of chronic spinal paralysis: Overview and initial clinical translation

Introduction There is at present no biological cure for chronic paralysis following spinal cord injury (SCI). A medley of experimental approaches have been tried over the years, and, despite some…

read more
Get Clinical Tree app for offline access