Genetics of Anorexia Nervosa
Anorexia nervosa (AN) is a debilitating and often refractory eating disorder that is unique among psychiatric disorders insofar as nutrition is key to recovery. Treatment options and efficacy are limited…
Tourette Syndrome and Chronic Tic Disorders
Tourette syndrome (TS) and chronic tic disorder (CTD) are characterized by persistent verbal and motor tics of varying severity. We describe modern genetic studies of TS/CTD focused on common and…
Psychiatric Pharmacogenomic Testing
Pharmacogenomic (PGx) testing is an evidence-based strategy to optimize the selection and dosing of certain psychotropic medications. An individual’s genetics play a role in medication response through pharmacokinetic and pharmacodynamic…
Ethical Considerations in Psychiatric Genomics
The ethics of psychiatric genetics and genomics is an emerging field, distinct from general genetics. Key ethical concerns include the implications for personhood and identity, the dual perception of psychiatric…
Diversifying Psychiatric Genomics
The underrepresentation of non-European researchers, participants, and datasets in psychiatric genetics hinders the understanding of mental health conditions and perpetuates health inequities. Ancestral diversity in research is crucial for advancing…
Psychiatric Genomics 2025
Psychiatric genetics has evolved from candidate-gene studies to whole-genome sequencing efforts. With hundreds of disease-associated loci now identified, functional interpretation of the associated loci becomes the critical next step toward…
Anatomo-electro-clinical Correlations
Acknowledgments The authors thank all staff and patients from their Epilepsy Monitoring Units. Introduction Jean Bancaud, who greatly contributed to the study of seizure semiology through his observations from the…
From SEEG Explorations to Surgical Interventions
Introduction The fundamental objective of SEEG is to facilitate the strategic planning and execution of surgical intervention(s) aimed at cessation of epileptic activity, translated into seizure freedom or at least…
The Utility of Stereoelectroencephalography in Lesional Epilepsy
Acknowledgments The author would like to extend sincere thanks to Professor Chauvel and Professor McGonigal for their insightful comments, and invaluable guidance. Introduction Epilepsy surgery stands as a transformative therapeutic…
Electrical Stimulation for Functional Mapping During SEEG Exploration
Introduction The challenge in epilepsy surgery is to cure the patient without causing an additional neurological deficit, so the maxim “primum non nocere” should be kept in mind throughout the…
