Psychomotor Retardation and Regression
Psychomotor retardation or developmental delay refers to the slow progress in the attainment of developmental milestones. This may be caused by either static ( Box 5-1 ) or progressive (…
Increased Intracranial Pressure
The presenting complaint when dealing with increased intracranial pressure ( Box 4-1 ) varies with age. Infants may present with bulging fontanelle, macrocephaly or failure to thrive. Older children often…
Altered States of Consciousness
The terms used to describe states of decreased consciousness are listed in Table 2-1 . With the exception of coma, these definitions are not standard. However, they are more precise…
Paroxysmal Disorders
Paroxysmal disorders are characterized by the sudden onset of neurological dysfunction and stereotyped recurrence. In children, such events often clear completely. Examples of paroxysmal disorders include epilepsy, migraine, periodic paralysis,…
Sarcoma Patient Advocacy: Hope and Help
Abstract Patient advocacy is the endeavor where laypeople advocate for patients, survivors, and caregivers inside the healthcare ecosystem. Patient advocates take on many roles in support of their patient community….
The Chordoma Foundation
Abstract The Chordoma Foundation (CF) is a global nonprofit organization whose mission is to improve the lives of those affected by chordoma and lead the search for a cure. The…
Prognosis, Survival, and Surveillance
Abstract Chordomas and chondrosarcomas are rare, typically slow-growing tumors; although individual patients can experience a considerably varied disease course. Understanding key prognostic factors can be a critical element in counseling…
Chordomas and Chondrosarcomas of the Axial Skeleton: Emerging Therapies and Future Directions
Abstract Chordoma and chondrosarcoma are related malignant bone tumors with some unusual features, such as their ability to dedifferentiate into high-grade sarcoma and abundance of extracellular matrix. Surgery remains the…
Recurrent Skull Base Chordomas: Role of Surgery
Abstract Skull base chordomas have a notorious tendency to recur even after wide radical removal of the soft tissue and osseous tumor and extensive drilling removal of surrounding bone. Their…
