Introduction Modern transsphenoidal approaches began with the contributions of Jules Hardy, who built on the legacy of earlier transsphenoidal approaches from Cushing’s to Norman Dott to Gerard Guiot. Hardy introduced…
Introduction Performing the transsphenoidal procedure requires the neurosurgeon to master a unique set of surgical techniques. While the ultimate goal rests with the hypophysis and neuraxis, the surgical approach mandates…
Introduction Like many advances in medicine, the transsphenoidal procedure as we know it today is the result of a long, relentless process. Many bold and creative pioneer surgeons have contributed…
Introduction The transsphenoidal approach to pituitary tumors represents a fascinating chronicle in surgical history. The result of this evolution and continued refinement of the transsphenoidal approach is that pituitary tumors…
Introduction Patients having transsphenoidal surgery offer many unique challenges to the anesthesiologist. Because of the prominent role of the pituitary gland in the endocrine system, patients require meticulous preoperative assessment,…
Introduction The goals of definitive surgical treatment of pituitary lesions are the reversal of endocrinopathy and restoration of normal pituitary function; elimination of mass effect and restoration of normal neurological…
Jules Hardy Over the last 10 years, numerous articles have reviewed the historical background of the surgical treatment of pituitary tumors and confronted the challenge between the alternative of intracranial versus…
Abstract The central nervous system (CNS) and its covering membranes may become involved with a variety of infectious processes in the newborn infant. These infections may occur either in the…
Abstract Hypoxic-ischemic encephalopathy in the perinatal period is a common disorder that has an impact throughout the perinatal period in both the preterm and term-born infant. Hypoxic-ischemic encephalopathy is characterized…
Abstract Disorders of muscle account for a substantial proportion of infants affected with hypotonia and weakness. Although a relatively large number of myopathic disorders may cause manifestations in the neonatal…
