Abstract Germinal matrix hemorrhage–intraventricular hemorrhage (GMH-IVH) is the most common variety of neonatal intracranial hemorrhage and is characteristic of the premature infant. This form of brain injury affects around 25%…
Abstract Bacterial infections of the central nervous system (CNS) in the newborn are common and are of major clinical importance. By far the most frequent of these infections is neonatal…
Abstract This chapter is focused on injuries of extracranial, cranial, intracranial, spinal cord, and peripheral nervous system structures, with emphasis on those disorders that appear to be related primarily to…
Abstract Neonatal encephalopathy occurs in 2 to 5/1000 live births and is principally related to hypoxic-ischemic injury to the newborn brain in the immediate peripartum period. In the last decade,…
Abstract The major unifying clinical manifestations of disorders of the neonatal motor system are hypotonia and weakness, which do not necessarily occur with similar severity. In this chapter, all disorders,…
Abstract Degenerative disorders of the newborn are relatively rare. Nonetheless, they are important to recognize because a few are treatable when diagnosed early. Dividing these disorders into those that primarily…
Abstract Drugs can exert major effects on the developing central nervous system (CNS). In the broadest sense, drugs may disturb specific developmental events in the brain and, in turn, produce…
Abstract Neuromuscular disorders may cause dramatic disability in the neonatal period. The dominant features of these disorders are muscle weakness and hypotonia. In this context, we consider as neuromuscular disorders…
Abstract Seizures represent the most distinctive and frequent manifestations of neurological disease in the neonatal period. Compared with seizures in older patients, neonatal seizures have different clinical appearances, electrographic characteristics,…
