Hippocampal Transections for Epilepsy
Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given…
History and Technical Approaches and Considerations for Ablative Surgery for Epilepsy
Key points • From post-traumatic epilepsy to non–lesional epilepsy, the history of epilepsy surgery has proceeded through phases of refined methods of localization of macroscopic and microscopic pathology. • Current…
Selective Amygdalohippocampectomy
Mesial temporal lobe epilepsy is a common condition that is frequently drug resistant. Anterior temporal lobectomy has been shown to be effective in controlling seizures but entails resecting anterior and…
Minimally Invasive Epilepsy Surgery
Kareem A. Zaghloul, MD, PhD, Editor Edward F. Chang, MD, Editor Refractory seizures in patients with epilepsy are associated with significant morbidity, cognitive decline, and premature death. For many patients,…
Medical Management of Meningiomas
Meningiomas are benign tumors of the central nervous system, with low recurrence risk for World Health Organization (WHO) grade I lesions but a high risk for WHO grade II and…
Management of Atypical and Anaplastic Meningiomas
Meningiomas are the most prevalent primary tumor of central nervous system origin and, although most neoplasms are benign, a small proportion exemplifies an aggressive profile characterized by high recurrence rates,…
Incidental Meningiomas
The number of patient imaging studies has increased because of precautious physicians ordering scans when a vague symptom is presented; subsequently, the number of incidental meningiomas detected has increased as…
The Contemporary Role of Stereotactic Radiosurgery in the Treatment of Meningiomas
Meningiomas are among the most common intracranial tumors in adults. The mainstay of treatment has been extirpation. Stereotactic radiosurgery (SRS) is an important option in the management of inaccessible, recurrent,…
Endoscopic Endonasal and Keyhole Surgery for the Management of Skull Base Meningiomas
The resection of anterior skull base meningiomas has traditionally been performed via pterional or unilateral/bilateral subfrontal craniotomies. The supraorbital keyhole approach and the endoscopic endonasal approach, techniques in which the…
