Medical Management of Brain Metastases
The main objective of treating brain metastases is to improve survival and to reduce symptom burden, preserve function, and enhance quality of life. As such, concurrent local control of existing…
The Molecular Pathobiology of Metastasis to the Brain: A Review
As the length of survival continues to improve for patients with systemic cancers, the problem of metastases to the chemotherapeutic sanctuary of the central nervous system (CNS) continues to grow….
Epidemiology of Metastatic Brain Tumors
Metastatic tumors are the most common brain tumors in adults, and their incidence is increasing. An accurate understanding of the epidemiology of metastatic brain tumors is useful for health care…
Development of a Clinical Functional Magnetic Resonance Imaging Service
One of the limitations of anatomy-based imaging approaches is its relative inability to identify whether specific brain functions may be compromised by the location of brain lesions or contemplated brain…
Identification of Neural Targets for the Treatment of Psychiatric Disorders: The Role of Functional Neuroimaging
Neurosurgical treatment of psychiatric disorders has been influenced by evolving neurobiological models of symptom generation. The advent of functional neuroimaging and advances in the neurosciences have revolutionized understanding of the…
Intraoperative Acquisition of fMRI and DTI
Multimodal functional navigation enables removing a tumor close to eloquent brain areas with low postoperative deficits, whereas additional intraoperative imaging ensures that the maximum extent of the resection can be…
Diffusion Tractography: Methods, Validation and Applications in Patients with Neurosurgical Lesions
Diffusion tensor imaging (DTI) tractography is increasingly used in presurgical mapping in tumors located in eloquent areas since it is the only non invasive technique that permits in vivo dissection…
Transcranial Brain Stimulation: Clinical Applications and Future Directions
Noninvasive brain stimulation is a valuable investigative tool and has potential therapeutic applications in cognitive neuroscience, neurophysiology, psychiatry, and neurology. Transcranial magnetic stimulation (TMS) is particularly useful to establish and…
Motor and Sensory Mapping
Functional magnetic resonance imaging (fMRI) enhances the understanding of neuroanatomy and functions of the brain and is becoming an accepted brain-mapping tool for clinicians, researchers, and basic scientists alike. A…
Preoperative Prediction of Verbal Episodic Memory Outcome Using fMRI
This article focuses on an important neurosurgical problem for which functional imaging may have a role. Temporal lobe epilepsy surgery typically involves removal of much of the anterior medial temporal…
