Intracranial Electroencephalography and Localization Studies Selim R. Benbadis Elaine Wyllie William E. Bingaman In recent years, as new neuroimaging techniques have revealed hippocampal sclerosis, focal cortical dysplasia, and other subtle…
Metabolic and Functional Neuroimaging William D. Gaillard Functional imaging studies using radiotracers, such as positron emission tomography (PET) and single-photonemission computed tomography (SPECT), are performed to identify or confirm the…
The Intracarotid Amobarbital Procedure Max R. Trenerry David W. Loring The preoperative evaluation of patients for epilepsy surgery typically includes electroencephalographic (EEG) monitoring, magnetic resonance imaging (MRI), neurologic examination, neuropsychological…
Magnetic Resonance Imaging Techniques in the Evaluation for Epilepsy Surgery Susanne Knake P. Ellen Grant Approximately 60% of all patients with epilepsy (0.4% of the population in industrialized countries) suffer…
Recognition of Potential Surgical Candidates and Video-Electroencephalographic Evaluation Gregory D. Cascino In the United States, 1% to 4% of the population has epilepsy—i.e., two or more unprovoked seizures, and approximately…
Issues of Medical Intractability for Surgical Candidacy Patrick Kwan Martin J. Brodie INTRODUCTION Although the effectiveness of epilepsy surgery for patients with surgically remediable syndromes refractory to antiepileptic drug (AED)…
Vagus Nerve Stimulation Therapy James W. Wheless Epilepsy and seizures affect at least 2.3 million individuals in the United States (1). Although antiepileptic drugs (AEDs) are the primary form of…
The Ketogenic Diet Douglas R. Nordli Jr. Darryl C. De Vivo INTRODUCTION The ketogenic diet is a high-fat, low-carbohydrate, low-protein regimen that has been used for more than 70 years…
Less Commonly Used Antiepileptic Drugs Basim M. Uthman Ahmad Beydoun INTRODUCTION Despite the availability of a large number of marketed antiepileptic drugs (AEDs), physicians use only a few to treat…
Newer Antiepileptic Drugs Norman Delanty Jacqueline A. French Despite advances and optimal current therapy, there remains a continuing need for the development of new agents for patients with epilepsy (1,…
