Psychiatric genetics has evolved from candidate-gene studies to whole-genome sequencing efforts. With hundreds of disease-associated loci now identified, functional interpretation of the associated loci becomes the critical next step toward…
Acknowledgments The authors thank all staff and patients from their Epilepsy Monitoring Units. Introduction Jean Bancaud, who greatly contributed to the study of seizure semiology through his observations from the…
Introduction The fundamental objective of SEEG is to facilitate the strategic planning and execution of surgical intervention(s) aimed at cessation of epileptic activity, translated into seizure freedom or at least…
Acknowledgments The author would like to extend sincere thanks to Professor Chauvel and Professor McGonigal for their insightful comments, and invaluable guidance. Introduction Epilepsy surgery stands as a transformative therapeutic…
Introduction The challenge in epilepsy surgery is to cure the patient without causing an additional neurological deficit, so the maxim “primum non nocere” should be kept in mind throughout the…
Stereoelectroencephalography (SEEG)-based presurgical evaluation of epilepsies has a double objective: to localize the epileptogenic zone (EZ) and to specify a surgical plan. Direct electrical stimulations from the intracerebral electrodes are…
Introduction The epileptogenic zone (EZ) concept arises from the stereoelectroencephalography (SEEG) method introduced by Talairach and Bancaud. , The term “EZ” was proposed by Bancaud and defined as “the regions…
Acknowledgments We thank John Seymour of UTHealth Houston Department of Neurosurgery, Salvadore Dural-Bernal of SUNY Downstate Health Sciences Center, and Takfarinas Medani of the University of Southern California Signal &…
Stereoelectroencephalography (SEEG) concepts are directed toward the precise identification of the parcel of the cortical ribbon responsible for seizure genesis in patients with drug resistant epilepsy. The phase I preoperative…
Introduction SEEG is a stereotaxic method that embraces a stereotactic technique In the SEEG method, as the main goal is to acquire precise anatomical localization of inter-ictal and ictal activities,…
