Harm from Stenting of Symptomatic Intracranial Arterial Stenoses Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenoses Chimowitz MI, Lynn MJ, Derdeyn CP, et al; SAMMPRIS Trial Investigators. NEJM. 2011;365:993-1003…
Mechanical Thrombectomy for Large Vessel Occlusion A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke Berkhemer OA, Fransen PSS, Beumer D, et al. NEJM. 2015;372:11-20 BACKGROUND Large artery occlusions…
Aspirin for Secondary Stroke Prevention Collaborative Overview of Randomised Trials of Antiplatelet Therapy—I: Prevention of Death, Myocardial Infarction, and Stroke by Prolonged Antiplatelet Therapy in Various Categories of Patients Antiplatelet…
Intravenous tPA for Acute Ischemic Stroke Tissue Plasminogen Activator for Acute Ischemic Stroke The National Institute of Neurological Disorders and Stroke rt-PA Study Group. NEJM. 1995;333(24):1581-1587 BACKGROUND At the time…
In this chapter we present additional disorders that can cause memory loss and other cognitive impairment. Although some of these disorders are common, because none are causes of dementia per…
Quick Start Cholinesterase Inhibitors Mechanism of action and cognitive benefit • Cholinesterase inhibitors increase the concentration of acetylcholine at the synapse and improve memory, attention, mood, and behavior. • Cholinesterase…
Because of the rapid aging of the population and the accompanying increase in the prevalence of Alzheimer’s disease, there is enormous interest from both the federal government and private industry…
In our experience, treatment of Alzheimer’s disease and other causes of memory loss and dementia is best carried out in a partnership between the patient, his or her caregiver(s), and…
Memantine (Namenda) was approved by the FDA for the treatment of moderate to severe Alzheimer’s disease in 2003. In 2014 twice-daily Namenda was discontinued, once-daily Namenda extended-release (XR) was introduced,…
Quick Start Special Issues in Memory Loss, Alzheimer’s Disease, and Dementia Some Patients Do Not Want to Have Their Memory Evaluated • Help patients understand that the goal is to…
