NEUROLOGY

Principles of Epilepsy Diagnosis and Management

Oct 11, 2017 by in NEUROLOGY Comments Off on Principles of Epilepsy Diagnosis and Management

  Recurrence rate (%) After first unprovoked seizure 40 After two unprovoked seizures 73 After three unprovoked seizures 76 After treating first unprovoked seizure 15 Table 15.2 Risk of seizure recurrence…

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Quality of Life in Epilepsy

Oct 11, 2017 by in NEUROLOGY Comments Off on Quality of Life in Epilepsy

© Springer Science+Business Media LLC 2017Mohamad Z. Koubeissi and Nabil J. Azar (eds.)Epilepsy Board Review10.1007/978-1-4939-6774-2_27 27. Quality of Life in Epilepsy Patsy J. Ramey1, Mohamad Z. Koubeissi1   and Nabil J. Azar1   (1) Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37212,…

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Procedures and Outcomes in Epilepsy Surgery

Oct 11, 2017 by in NEUROLOGY Comments Off on Procedures and Outcomes in Epilepsy Surgery

© Springer Science+Business Media LLC 2017Mohamad Z. Koubeissi and Nabil J. Azar (eds.)Epilepsy Board Review10.1007/978-1-4939-6774-2_26 26. Procedures and Outcomes in Epilepsy Surgery Ronald P. Lesser1   (1) Department of Neurology, Johns Hopkins University School of Medicine, 600 North…

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Status Epilepticus

Oct 11, 2017 by in NEUROLOGY Comments Off on Status Epilepticus

Generalized Convulsive Non-convulsive Focal Convulsive (epilepsia partialis continua) Non-convulsive Non-epileptic (“Pseudo-SE”)  The task force on SE of the ILAE Commission on European Affairs has suggested a more exhaustive classification, as…

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Neuropsychological Evaluation in Epilepsy

Oct 11, 2017 by in NEUROLOGY Comments Off on Neuropsychological Evaluation in Epilepsy

Domain Common measures—but not exhaustive list Skill All (most) ages Adult version Pediatric version Intellectual functioning   Wechsler Abbreviated Scale of Intelligence-Second Edition (WASI-II)  Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV)…

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Epilepsy Management in Special Populations

Oct 11, 2017 by in NEUROLOGY Comments Off on Epilepsy Management in Special Populations

© Springer Science+Business Media LLC 2017Mohamad Z. Koubeissi and Nabil J. Azar (eds.)Epilepsy Board Review10.1007/978-1-4939-6774-2_20 20. Epilepsy Management in Special Populations Amir M. Arain1   (1) Vanderbilt University, A-0118 Medical Center North, Nashville, TN 37232, USA     Amir M. Arain…

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Other Pharmacological Therapies: Investigational Antiepileptic Drugs, Animal Models of Epilepsy, Hormonal Therapy, Immunotherapy

Oct 11, 2017 by in NEUROLOGY Comments Off on Other Pharmacological Therapies: Investigational Antiepileptic Drugs, Animal Models of Epilepsy, Hormonal Therapy, Immunotherapy

Animal model MES PTZ Kindling DBA/2 mice GAERS rats Human seizure/epilepsy type Generalized tonic-clonic seizures Generalized absence seizures Partial seizures (limbic) Generalized tonic-clonic, reflex seizures, SUDEP Generalized absence seizures Animal…

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Dietary Therapies

Oct 11, 2017 by in NEUROLOGY Comments Off on Dietary Therapies

© Springer Science+Business Media LLC 2017Mohamad Z. Koubeissi and Nabil J. Azar (eds.)Epilepsy Board Review10.1007/978-1-4939-6774-2_18 18. Dietary Therapies Amy Kao1   (1) Center for Neurosciences and Behavioral Medicine, Children’s National Health System, 111 Michigan Ave NW, Washington,…

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New-Generation Antiepileptic Drugs

Oct 11, 2017 by in NEUROLOGY Comments Off on New-Generation Antiepileptic Drugs

AED Felbamate Gabapentin Lamotrigine Topiramate Tiagabine Levetiracetam Protein bindinga Low Low Intermediate Low High Low Half-lifeb Intermediate Short Intermediate Intermediate Short Short Metabolism ~50% None Extensive ~30% Extensive ~30% Not…

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Old-Generation Antiepileptic Drugs

Oct 11, 2017 by in NEUROLOGY Comments Off on Old-Generation Antiepileptic Drugs

AED Phenytoin Carbamazepine Oxcarbazepine MHD Phenobarbital Valproate Ethosuximide Protein bindinga High Intermediate Low Low High Low Half-lifeb Intermediate (can become long in toxicity) Intermediate Short Long Intermediate Long Metabolism Extensive,…

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