ID Study Sponsor (country) 1st received Condition of patients Cell source (product code) Delivery route Phase Status of trials NCT00473057 Study of Autologous Stem Cell Transplantation for Patients With Ischemic…
Fig. 4.1 Summary of induction of iPSCs, iNSCs, and iNCs and direct in vivo reprogramming (Modified from Yamashita et al. [28]). (a) Overexpression of Oct3/4, Sox2, Klf4, and c-Myc can…
Fig. 1.1 Overview of the proposed mechanisms of bone marrow-derived mononuclear cell (MNC)-based stroke therapies. Cells transplanted by intravenous (IV) or intra-arterial (IA) injection migrate toward the ischemic boundary zone…
© Springer Japan KK 2017Kiyohiro Houkin, Koji Abe and Satoshi Kuroda (eds.)Cell Therapy Against Cerebral Stroke10.1007/978-4-431-56059-3_7 7. Role of Biomaterials as Scaffolding in Cell Therapy for Stroke Toshiya Osanai1 (1) Department of Neurosurgery, Hokkaido University Graduate School…
© Springer Japan KK 2017Kiyohiro Houkin, Koji Abe and Satoshi Kuroda (eds.)Cell Therapy Against Cerebral Stroke10.1007/978-4-431-56059-3_2 2. Cell Therapy for Ischemic Stroke with Bone Marrow Stromal Cells Satoshi Kuroda1, 2 , Hideo Shichinohe2 and Kiyohiro Houkin2 (1) Department of Neurosurgery,…
Fig. 6.1 Schematic drawing of the transplantation route with its advantage and disadvantage 6.2.1 Intravenous Route One of the major advantages of using intravenous route for cell transplantation is its…
Author Year Conditions being studied Study type Cell transplantation procedures Stroke type Timing of delivery after stroke Phase category Location Cell type Cell source Delivery route Kondziolka et al. 2000…
, Mark Gorman2 and Salman Al Jerdi2 (1) Department of Cardiovascular Medicine and Electrophysiology, Yale School of Medicine, Yale-New Haven Hospital, New Haven, CT, USA (2) Department of Cardiovascular Medicine, Yale School of…
Figure 13-1 Hypertensive hemorrhage: A 47-year-old male with hypertensive urgency – large, acute hematoma in the right basal ganglia with mild perilesional edema causing mass effect, midline shift, and subfalcine…
Atrial fibrillation Mechanical prosthetic valve Left atrial appendage thrombus Left ventricular thrombus Anterior wall MI Endocarditis Aortic sclerosis Dilated cardiomyopathy PFO /atrial septal aneurysm Atrial flutter Mitral stenosis Aortic dissection…
