Trigeminal autonomic cephalalgias (TACs) encompass a group of primary headache disorders characterized by unilateral headache with ipsilateral cranial autonomic symptoms such as conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial sweating,…
Prophylactic therapy for migraine is aimed at reducing the frequency, and possibly severity, of recurrent migraine headaches. To maximize tolerability, it is important to start with low doses and titrate…
Acute treatment of migraine should target both head pain and, if present, associated symptoms such as nausea and vomiting. The latter may limit absorption of oral medications; in these cases,…
While the initial neurologic symptoms following concussion typically resolve quickly, many will have symptoms that evolve over the ensuing 1–3 days. The majority of patients experience a complete recovery in…
Initial primary brain injury following trauma occurs immediately at the time of head impact and is largely irreversible. Public health measures such as airbags, seat belts, bike helmets, and fall…
A. Concussion, more appropriately called mild traumatic brain injury, refers to any trauma-induced alteration in brain function. An obvious corollary of this is that patients must have head trauma causing…
A. Paroxysmal sympathetic hyperactivity (PSH) is a syndrome encountered in patients with severe acute neurologic injury. Patients with PSH may have episodic tachycardia, hypertension, tachypnea, fever, diaphoresis, and posturing. Episodes…
Patients with neuromuscular disease presenting with severe weakness require close monitoring of their respiratory status, as progression to respiratory failure can occur relatively suddenly. As the fundamental problem is one…
Brain tissue, cerebrospinal fluid (CSF), and blood are contained within the confined space of the skull. An increase in volume of one of these components necessarily results in a compensatory…
A. Brain death is defined, in the United States and many other countries, as permanent and irreversible cessation of whole brain function. Some countries, such as the United Kingdom, consider…
