NEUROLOGY

Cerebral Venous Thrombosis

Dec 16, 2016 by in NEUROLOGY Comments Off on Cerebral Venous Thrombosis

Fig. 10.1 Acute phase of deep venous thrombosis (right thalamostriate vein). The FLAIR sequence (a) shows the venous infarction with very limited hyperintensity on diffusion-weighted images (c) related to predominantly vasogenic…

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Lacunar Infarcts and Small-Vessel Disease

Dec 16, 2016 by in NEUROLOGY Comments Off on Lacunar Infarcts and Small-Vessel Disease

Fig. 6.1 Hyperintense lacunar infarct in the left lateral sulcus on diffusion-weighted images (a hollow arrow). It is associated with multiple lacunar infarct sequelae as “holes” in the brain parenchyma, hypointense…

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Transient Ischaemic Attacks

Dec 16, 2016 by in NEUROLOGY Comments Off on Transient Ischaemic Attacks

Fig. 5.1 Patient with right carotid TIA. MR angiography (a axial section, b sagittal reconstruction) shows unstable plaque of right carotid bulb with endoluminal fragment (arrow). REC right external carotid artery, RIC…

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Systems Phenomics

Dec 16, 2016 by in NEUROLOGY Comments Off on Systems Phenomics

Fig. 7.1 Magnetic resonance images of a 24-week-old foetus. From Anblagan et al. (unpublished observation) The same scanner can be used for acquiring different types of images by changing the exact…

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Personalized Preventive Medicine

Dec 16, 2016 by in NEUROLOGY Comments Off on Personalized Preventive Medicine

Fig. 10.1 Healthy and total (healthy + unhealthy) life expectancy at birth in England, 1994–1999. Adapted from the Office for National Statistics licensed under the Open Government Licence v.1.0. From Bajekal (2005) Given…

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Challenges

Dec 16, 2016 by in NEUROLOGY Comments Off on Challenges

Fig. 9.1 Meta-analysis of the effects of breastfeeding on cognitive development. Numbers indicate co-variate-adjusted mean differences (and 95 % confidence intervals) for matched composite observations across 11 different studies. Reprinted from Anderson…

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Genomics

Dec 16, 2016 by in NEUROLOGY Comments Off on Genomics

Fig. 4.1 DNA–chromatin complexes a binding of basic histone proteins, b a nucleosome—two turns of DNA wrapped around core histones, c electron micrograph of nucleosomal filaments, d cross section of a…

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Enviromics

Dec 16, 2016 by in NEUROLOGY Comments Off on Enviromics

Fig. 3.1 An individual and his/her internal, social and physical environments Because the cells of various tissues are exposed to hundreds of small molecules (metabolites), hormones and enzymes circulating through the…

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Terms and Concepts

Dec 16, 2016 by in NEUROLOGY Comments Off on Terms and Concepts

Fig. 1.1 Breastfeeding and general intelligence: mediation and moderation From this pattern of “transactions”, we conclude that exposure (breastfeeding) affects the outcome (general intelligence) by influencing mediator 1 (brain growth inferred…

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Epigenomics

Dec 16, 2016 by in NEUROLOGY Comments Off on Epigenomics

Fig. 5.1 Agouti mice. From Morgan et al. (1999) Such trans-generational epigenetic transmission is likely to vary with the number of subsequent generations. For example, certain epigenetic modifications of histones in…

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