NEUROLOGY

Physiology and Constituents of CSF

Dec 11, 2016 by in NEUROLOGY Comments Off on Physiology and Constituents of CSF

Fig. 3.1 Relationship between CSF–serum ratio of blood (white circles) and brain-derived (black circles) compounds and their hydrodynamic radius under “steady-state” conditions (Modified according to Felgenhauer (1995)). Alb albumin, α2-M…

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Special Techniques

Dec 11, 2016 by in NEUROLOGY Comments Off on Special Techniques

and Cheng-Ying Ho2 (1) Pathology, Johns Hopkins University, Baltimore, Maryland, USA (2) Pathology, Children’s National Medical Center, Washington, D.C., District of Columbia, USA   General Considerations Routine biomarkers in use in…

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Biomarkers Applied to Specific Tumor Types

Dec 11, 2016 by in NEUROLOGY Comments Off on Biomarkers Applied to Specific Tumor Types

and Cheng-Ying Ho2 (1) Pathology, Johns Hopkins University, Baltimore, Maryland, USA (2) Pathology, Children’s National Medical Center, Washington, D.C., District of Columbia, USA   Diffuse Gliomas in Adults Clinical and Pathologic…

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Introduction

Dec 11, 2016 by in NEUROLOGY Comments Off on Introduction

and Cheng-Ying Ho2 (1) Pathology, Johns Hopkins University, Baltimore, Maryland, USA (2) Pathology, Children’s National Medical Center, Washington, D.C., District of Columbia, USA   Current Biomarkers in Neoplastic Neuropathology Enormous advances…

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Public Databases

Dec 11, 2016 by in NEUROLOGY Comments Off on Public Databases

and Cheng-Ying Ho2 (1) Pathology, Johns Hopkins University, Baltimore, Maryland, USA (2) Pathology, Children’s National Medical Center, Washington, D.C., District of Columbia, USA   General Considerations One of the main advantages…

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Biobanking and Regulations

Dec 11, 2016 by in NEUROLOGY Comments Off on Biobanking and Regulations

and Cheng-Ying Ho2 (1) Pathology, Johns Hopkins University, Baltimore, Maryland, USA (2) Pathology, Children’s National Medical Center, Washington, D.C., District of Columbia, USA   General Considerations Biobanks are biorepositories of human…

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Gene Expression-Based Approaches to Understanding Huntington’s Disease and New Tools for the Interpretation of Expression Datasets

Dec 11, 2016 by in NEUROLOGY Comments Off on Gene Expression-Based Approaches to Understanding Huntington’s Disease and New Tools for the Interpretation of Expression Datasets

Fig. 1 Illustration of differential gene expression profiling in Huntington’s disease (HD) systems. In this approach, cumulative cellular events relating to the disease process are described by “molecular snapshots” that…

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Location Analysis and Expression Profiling Using Next-Generation Sequencing for Research in Neurodegenerative Diseases

Dec 11, 2016 by in NEUROLOGY Comments Off on Location Analysis and Expression Profiling Using Next-Generation Sequencing for Research in Neurodegenerative Diseases

Fig. 1 ChIP-seq workflow. Major steps in experimental procedure include cell collection and cross-linking, sonication of chromatin to achieve desired fragment length, antibody pulldown, library preparation, and sequencing 2 Materials…

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