Fig. 1 Average global cerebrovascular reactivity index (CVR) in SAH patients and controls. (a) Step 1, normocapnia; (b) Step 2, hypercapnia; and (c) Step 3, return to normocapnia Study Protocol…
Fig. 1 Effects of TNC on cerebral arteries during the 72-h observation period. (a) Representative India-ink angiograms 24 h after injection; arrow, left internal carotid artery (ICA). (b) Vessel diameter…
Characteristics* Total number of patients 21 Sex Male 6 (29) Female 15 (71) Male/female rate 0.4 Mean age (years) 52.8 ± 16.5 Range (years) 19–78 Presentation Unruptured 9 (43) Ruptured 12 (57)…
Neurological complications Systemic complications Early phase Aneurysm rebleeding Stress-induced cardiomyopathy Acute hydrocephalus Pulmonary edema (neurogenic, cardiogenic) Seizures Cardiac arrhythmias Global edema/intracranial hypertension Acute hypertension Delayed phase Vasospasm Fever (central or…
Fig. 1 OxyHb and HB-EGF suppressed K V currents of cerebral artery myocytes from control animals but not from SAH model animals. (a) Example of whole-cell K+ currents before and…
Fig. 1 Modified Garcia Score at 24 and 48 h (maximum score of 18). The SAH group had significantly lower modified Garcia Scores at both 24 and 48 h compared…
Fig. 1 Third intervention for patient No. 5; DSA anterior/posterior projection. Note the typical additional effect on vasodilation of milrinone supplementary to nimpodipine (orange arrow M1 segment, yellow arrow A1…
Inclusion criteria Exclusion criteria Age ≥ 18 years old Nonaneurysmal hemorrhage Confirmed aSAH Unstable clinical condition Aneurysm secured (clipping or coiling) Aneurysm not secured (clipping or coiling) WFNS grade 1 or 2…
Fig. 1 Histogram of documented cerebral vasospasm. The greatest frequency of vasospasm was during days 11–14 (5 of 7 patients) Fig. 2 Changes in the metal cation concentration in the…
Fig. 1 Post SAH patient mortality and underlying mechanisms: mortality in SAH patients is greatest in the early phase (a). Although early mortality results from early activating mechanisms, delayed mortality…
