Epilepsy Surgery in Infants and Children Ajay Gupta Elaine Wyllie William E. Bingaman Surgery is now a well-established treatment for adults and children with medically intractable seizures (1, 2, 3,…

Epilepsy Surgery in the Absence of a Lesion on Magnetic Resonance Imaging Elson L. So Magnetic resonance imaging (MRI) is a prerequisite in the evaluation of patients for epilepsy surgery….

Hemispherectomy: Medications, Technical Approaches, and Results José Luis Montes Jean-Pierre Farmer Frederick Andermann Chantal Poulin HISTORICAL AND BACKGROUND CONSIDERATIONS Walter Dandy first described hemispherectomy as a surgical technique in 1928…

Epilepsy Surgery in Focal Malformations of Cortical Development Jorge A. González-Martánez Imad M. Najm William E. Bingaman Paul Ruggieri Focal malformations caused by abnormal cortical development (MCD) are the pathologic…

Resection for Uncontrolled Epilepsy in the Setting of Focal Lesions on MRI: Tumor, Vascular Malformation, Trauma, and Infarction Dennis D. Spencer Alexandre C. Carpentier Advances in neuroimaging techniques, particularly high-resolution…

Hippocampal Sclerosis and Dual Pathology Evan J. Fertig Susan S. Spencer Over the past several decades, technical advances have revolutionized the surgical treatment of medically refractory epilepsy, allowing precise localization…

Intracranial Electroencephalography and Localization Studies Selim R. Benbadis Elaine Wyllie William E. Bingaman In recent years, as new neuroimaging techniques have revealed hippocampal sclerosis, focal cortical dysplasia, and other subtle…

Metabolic and Functional Neuroimaging William D. Gaillard Functional imaging studies using radiotracers, such as positron emission tomography (PET) and single-photonemission computed tomography (SPECT), are performed to identify or confirm the…

Magnetic Resonance Imaging Techniques in the Evaluation for Epilepsy Surgery Susanne Knake P. Ellen Grant Approximately 60% of all patients with epilepsy (0.4% of the population in industrialized countries) suffer…