Spastic Gait/Dysarthria Due to Primary Progressive Multiple Sclerosis OBJECTIVES To discuss primary progressive multiple sclerosis (MS). To discuss the treatment of primary progressive MS. VIGNETTE This 65-year-old man presented with…
Multiple Sclerosis (Pontine Lesion) OBJECTIVES To discuss the clinical manifestations of a pontine lesion. To discuss ancillary tests used to diagnose multiple sclerosis (MS). VIGNETTE A 35-year-old man was admitted…
Nystagmus/Ataxia Secondary to Relapsing-Remitting Multiple Sclerosis OBJECTIVES To discuss relapsing-remitting multiple sclerosis (MS). To discuss the treatment of MS. VIGNETTE A 27-year-old African-American woman had several episodes of neurologic deficits….
Bilateral Internuclear Ophthalmoplegia Secondary to Multiple Sclerosis OBJECTIVES To briefly discuss multiple sclerosis. To highlight the main features of internuclear ophthalmoplegia (INO). VIGNETTE This 44-year-old woman had a history of…
Lipid Storage Ataxia: Niemann-Pick Type C OBJECTIVES To review the clinical features of Niemann-Pick C. To outline the differential diagnosis of the various forms of ataxia whose features may overlap…
Multiple System Atrophy, Cerebellar Type OBJECTIVES To review the clinical features of multiple system atrophy, cerebellar type (MSA-C). To outline the features most helpful in distinguishing this disorder from other…
Spinocerebellar Ataxia Type 3 OBJECTIVES To review the clinical features of spinocerebellar ataxia type 2 (SCA 3). To outline the features most helpful in distinguishing this form of ataxia from…
Hereditary Ataxia OBJECTIVES To review clinical features of hereditary cerebellar ataxia. To outline distinctive clinical features of common spinocerebellar ataxia (SCA) subtypes. VIGNETTE A 31-year-old woman had a progressive history…
Cerebellar Ataxia OBJECTIVES To review the clinical presentation of midline cerebellar dysfunction. To outline the differential diagnosis of acquired progressive cerebellar degeneration and summarize the appropriate laboratory evaluation. VIGNETTE Seven…
Friedreich Ataxia OBJECTIVES To present an example of Friedreich ataxia. To discuss the differential diagnosis of Friedreich ataxia. To summarize current management strategies for Friedreich ataxia. VIGNETTE This 24-year-old woman…
