15 Research About Neurofibromatosis Although the past decade has yielded many new insights into the genetic and molecular abnormalities that cause neurofibromatosis, many questions remain about how its manifestations develop…
14 Practical and Quality-of-Life Issues This chapter focuses on the major practical and quality-of-life aspects of living with neurofibromatosis (NF). Logistical challenges include coordinating multiple medical visits, navigating the insurance…
13 Psychosocial Impact of Neurofibromatosis Neurofibromatosis (NF) has a psychosocial impact that consists of psychological, social, economic, and quality-of-life issues. Psychosocial issues pervade the life of not only the individual…
1 Introduction and History Neurofibromatosis * is the umbrella term for three distinct genetic disorders that share a hallmark manifestation—tumor growth in the tissues that surround nerves. Most tumors are…
8 Cognitive Function and Learning Disabilities in Neurofibromatosis 1 Neurofibromatosis 1 (NF1) impacts brain development in ways that researchers are still trying to understand. About half of all people with…
4 Genetics and Genetic Counseling in Neurofibromatosis 1 and Neurofibromatosis 2 Molecular genetics explains how a mutation may cause a disorder. Clinical genetics takes a somewhat different perspective: how the…
7 Other Neural Tumors and Nervous System Abnormalities in Neurofibromatosis 1 As would be expected in a disorder caused by the loss of a tumor suppressor gene, neurofibromatosis 1 (NF1)…
Chapter 1 Introduction and overview Neuroanatomical terminology and conventions 1 Components and organisation of the nervous system 2 Neurones and neuroglia 2 Central and peripheral nervous systems 3 Somatic and autonomic nervous systems 3 Afferent…
Chapter 10 Cranial nerves and cranial nerve nuclei Cranial nerve nuclei 103 Afferent nuclei 103 Efferent nuclei 103 Cranial nerves 105 III: Oculomotor nerve 105 IV: Trochlear nerve 106 VI: Abducens nerve 107 V: Trigeminal nerve 107 VII:…
Chapter 8 Spinal cord External features of the spinal cord 69 Topographical anatomy 69 Spinal nerves 70 Spinal meninges 71 Internal structure of the spinal cord 73 Grey matter of the spinal cord 74 Spinal reflexes 76…
