Abstract Chordomas and chondrosarcomas are malignant tumors whose gross total resection significantly increases the overall survival. They are locally invasive; as they breach normal anatomic planes, chordomas and chondrosarcomas may…
Abstract Chordomas and chondrosarcomas of the skull base are pathologically and genetically distinct neoplasms that are often grouped together because of their similar radiologic, anatomical, and surgical features. Although rare…
Abstract The anatomic location and clinical behavior of chordomas and chondrosarcomas of the spine present unique challenges that require appropriate and thoughtfully planned surgical resection. These lesions generally affect adults…
Abstract Chordomas and chondrosarcomas are different histopathological entities with markedly different natural history and clinical outcomes. Sharing a similar clinical and radiological presentation, their definite identification is confirmed only by…
Abstract Until the last decade of the 20th century, craniocervical junction (CCJ) stabilization was achieved largely through simple instrumentation such as spinous process and lateral mass wiring. The introduction of…
Abstract Chordomas and chondrosarcomas are rare primary malignant spine tumors. In spite of recent advancements in chemotherapy, targeted therapy, and radiation therapy, surgery remains the gold standard for treatment of…
Abstract Resection of skull base chordomas and chondrosarcomas can create large dural defects that involve multiple cisterns or the third ventricle leading to high-flow cerebrospinal fluid leaks. Reconstruction of the…
Abstract Chordomas and chondrosarcomas of the spine share several key features that make them distinct from other malignant primary bone tumors. They manifest more indolent behavior characterized by slow but…
Abstract The craniovertebral junction is a complex region that includes the lower clivus, foramen magnum, C1, and C2. Chordomas and chondrosarcomas are slowly growing tumors that arise from notochord rests…
Abstract Chondrosarcomas and chordomas are the most common malignant primary bone tumors involving the spine. Surgery is usually the initial treatment of these tumors. In the past two decades, surgery…
