Barriers to Delivery of Therapeutics to Brain Tumors
CHAPTER 105 Barriers to Delivery of Therapeutics to Brain Tumors Dani S. Bidros, Michael A. Vogelbaum Malignant gliomas are the most common type of primary brain tumor in adults. According…
NEUROSURGERY
Patient Positioning for Spinal Surgery
CHAPTER 27 Patient Positioning for Spinal Surgery Peter D. Angevine, Paul R. Gigante, Paul C. McCormick To obtain optimal outcomes from spinal surgery, any operation must be performed effectively and…
Intracranial Ependymomas in Adults
CHAPTER 127 Intracranial Ependymomas in Adults James L. Frazier, George I. Jallo Intracranial ependymomas in adults are relatively rare brain tumors of neuroectodermal origin that account for 2% to 6%…
Surgical Treatment of Major Depression
CHAPTER 89 Surgical Treatment of Major Depression Clement Hamani, Brian Snyder, Adrian W. Laxton, Paul E. Holtzheimer, Helen S. Mayberg, Andres M. Lozano Depression is a prevalent and often debilitating…
Evaluation of Patients for Epilepsy Surgery
CHAPTER 56 Evaluation of Patients for Epilepsy Surgery Costas Michaelides, Garth Rees Cosgrove, Andrew J. Cole Up to 40% of epilepsy patients have medication-resistant or medically intractable seizures.1 As many…
Principles of Translation of Biologic Therapies in Spinal Cord Injury
CHAPTER 267 Principles of Translation of Biologic Therapies in Spinal Cord Injury James Guest Life can only be understood backward, but it must be lived forward. —Soren Kierkegaard The function…
Overview and Historical Considerations
CHAPTER 264 Overview and Historical Considerations Volker K.H. Sonntag, Dennis G. Vollmer, Christopher I. Shaffrey Spinal disorders have been recognized as a serious affliction of humans since ancient times. Early…
Cranioplasty
CHAPTER 32 Cranioplasty Robert G. Whitmore, Shabbar F. Danish, M. Sean Grady Skull defects and craniofacial bone abnormalities that require reconstruction are common in a variety of neurosurgical procedures. From…
Pallidal Interventions for Parkinson’s Disease
CHAPTER 79 Pallidal Interventions for Parkinson’s Disease Philip A. Starr The basal ganglia are a collection of subcortical nuclei involved in the focusing and scaling of movement. These nuclei participate…
Advantages and Limitations of Cranial Endoscopy
CHAPTER 30 Advantages and Limitations of Cranial Endoscopy Jeroen R. Coppens, William T. Couldwell Endoscopy was first used intracranially in the treatment of hydrocephalus at the beginning of the 20th…
